نتایج جستجو برای: Malva sylvestris Parkinson’s disease6-hydroxydopamine Motor asymmetry Dopaminergic neurons

تعداد نتایج: 356076  

Journal: :journal of basic and clinical pathophysiology 0
forogh dehghani department of biology, payame noor university,tehran, iran mehrdad roghani neurophysiology research center, shahed university, tehran, iran tourandokht baluchnejadmojarad department of physiology, school of medicine, iran university of medical sciences, tehran, iran

background and objective: parkinson’s disease (pd) is a common neurological disorder due to degeneration of dopaminergic neurons within pars compacta of substantia nigra (snc). with regard to protective effect of malva sylvestris (ms), this study was conducted to evaluate the effect of aquaeous extract of this plant in an experimental model of pd induced by 6-hydroxydopamine (6-ohda). materials...

Forogh Dehghani, Mehrdad Roghani* Tourandokht Baluchnejadmojarad

Background and Objective: Parkinson’s disease (PD) is a common neurological disorder due to degeneration of dopaminergic neurons within pars compacta of substantia nigra (SNC). With regard to protective effect of Malva sylvestris (MS), this study was conducted to evaluate the effect of aquaeous extract of this plant in an experimental model of PD induced by 6-hydroxydopamine (6-OHDA). Material...

Journal: :journal of basic and clinical pathophysiology 2015
tourandokht baluchnejadmojarad monireh mansouri farnaz nikbakht soudabeh fallah mehrdad roghani

background and objective: parkinson's disease (pd) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. l-dihydroxyphenylamine (l-dopa) therapy is currently the gold standard maneuver for pd. due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of this age...

Farnaz Nikbakht, Mehrdad Roghani, Monireh Mansouri, Soudabeh Fallah Tourandokht Baluchnejadmojarad

Background and Objective: Parkinson's disease (PD) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. L-dihydroxyphenylamine (L-DOPA) therapy is currently the gold standard maneuver for PD. Due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of this age...

Journal: :journal of basic and clinical pathophysiology 0
tourandokht baluchnejadmojarad department of physiology, school of medicine, iran university of medical sciences, tehran, iran monireh mansouri department of physiology, school of medicine, iran university of medical sciences, tehran, iran farnaz nikbakht department of physiology, school of medicine, iran university of medical sciences, tehran, iran soudabeh fallah department of biochemistry, school of medicine, iran university of medical sciences, tehran, iran mehrdad roghani neurophysiology research center, shahed university, tehran, iran

background and objective: parkinson's disease (pd) is an age-related neurodegenerative disease with selective damage of dopaminergic neurons of the mesencephalon. l-dihydroxyphenylamine (l-dopa) therapy is currently the gold standard maneuver for pd. due to the protective, anti-inflammatory, and antioxidant effect of sesamin, this study was undertaken to assess dose-dependent effect of thi...

ژورنال: دانشور پزشکی 2014
روغنی, مهرداد, قینی, محمدحسین , مس کار, حسین,

Background and Objective: Parkinson's disease is a common movement disorder in elders caused by depletion of dopaminergic neurons in the substantia nigra in midbrain. Due to antioxidant and neuroprotective properties of epigallocatechin gallate (EGCG), the present study investigated its neuroprotective effect in an experimental model of Parkinson's disease. Materials and Methods: In this exp...

Introdution: Parkinson's disease is the second most common neurodegenerative disease. Considering the antioxidant and neuroprotective properties of chlorogenic acid, the purpose of this study was to evaluate the neuroprotective effect of this substance in an experimental model of Parkinson's disease. Methods: In this experimental study, Wisar male rats (n = 32) were divided into 4 groups: sham...

ژورنال: دانشور پزشکی 2015
افشین مجد, سیامک, خلیلی , محسن, رحمتی, بتول, روغنی, مهرداد, قائدی, غلامحسین, کرمی, منیژه, کیاسالاری, زهرا,

Background and Objective: Parkinson's disease is a rather common movement disorder in aged individuals due to degeneration of dopaminergic neurons within the substantia nigra pars compacta. Due to antioxidant, anti-inflammatory and protective effects of the flavanone hesperetin, the present study assessed dose-dependent effect of hesperetin on motor asymmetry induced by intrastriatal injection ...

Journal: :journal of basic and clinical pathophysiology 2013
mahmoud salami razieh malekmohammadi seyed mojtaba banitaba mehrdad roghani

abstract background and objective: parkinson's disease (pd) is an age-related neurodegenerative disorder with massive loss of dopaminergic neurons in the substantia nigra pars compacta. l-dihydroxyphenylalanine (l-dopa) substitution is still the gold standard therapy for pd. however, there has been little information available on neuroprotective and regenerative therapies for pd. due to the neu...

ABSTRACT Background and Objective: Parkinson's disease (PD) is an age-related neurodegenerative disorder with massive loss of dopaminergic neurons in the substantia nigra pars compacta. L-Dihydroxyphenylalanine (L-DOPA) substitution is still the gold standard therapy for PD. However, there has been little information available on neuroprotective and regenerative therapies for PD. Due to the neu...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید