PURPOSE To assess the radiation dose delivered to the heart and ipsilateral lung during accelerated partial breast brachytherapy using a MammoSite applicator and compare to those produced by whole breast external beam radiotherapy (WBRT). MATERIALS AND METHODS Dosimetric analysis was conducted on patients receiving MammoSite breast brachytherapy following conservative surgery for invasive duc...

Accelerated partial breast irradiation is commonly done with the MammoSite applicator, which requires symmetry to treat the patient. This paper describes three cases that were asymmetric when initially placed and became symmetric over time, without manipulation.

HYPOTHESIS Balloon catheter-based accelerated partial breast irradiation (APBI) may result in desirable short-term outcomes in patients undergoing breast conserving surgery. DESIGN Prospective consecutive case series. SETTING Tertiary multidisciplinary referral center. PATIENTS Forty selected patients with invasive breast carcinoma undergoing breast conserving surgery and MammoSite device...

Introduction: In brachytherapy treatments, high-dose sources are used in interstitial placement. In this paper, the modeling of a common breast cancer treatment applicator called MammoSite is done by the Monte Carlo simulation code. Then, to study and calculate the amount of doses in the breast and the dose rate of the organs at risk of radiation, including: lungs, ribs and ski...

The Contura brachytherapy applicator is a silicone balloon with five lumens in which a high-dose-rate brachytherapy source can traverse. Multilumen applicators, like the Contura, are used in accelerated partial breast irradiation (APBI) brachytherapy in instances where asymmetric dose distributions are desired; for example, when the applicator surface-to-skin thickness is small (< 7 mm). In the...

PURPOSE To investigate the incidence of, and possible factors associated with, seroma formation after intraoperative placement of the MammoSite catheter for accelerated partial breast irradiation. METHODS AND MATERIALS This study evaluated 38 patients who had undergone intraoperative MammoSite catheter placement at lumpectomy or reexcision followed by accelerated partial breast irradiation wi...

PURPOSE To evaluate the dosimetric performance and clinical utility of the Strut-Adjusted Volume Implant (SAVI) (Cianna Medical, Aliso Viejo, CA) applicator when used as the sole method of radiation therapy for patients with early breast carcinoma. METHODS AND MATERIALS The dosimetric performance of a Phase II clinical trial has been reported using the SAVI applicator for patients with early ...

PURPOSE To review our institution's experience of treating patients with the MammoSite (Cytyc Corp., Marlborough, MA) breast brachytherapy catheter to deliver accelerated partial-breast irradiation (APBI), for determining short-term treatment efficacy, cosmesis, and toxicity. METHODS AND MATERIALS From January 2000 to April 2006, 80 patients treated with breast-conserving therapy (BCT) receiv...