The development of microreactors that operate under harsh conditions is always of great interest for many applications. Here we present a microfabrication process based on low-temperature co-fired ceramic (LTCC) technology for producing microreactors which are able to perform chemical processes at elevated temperature (>400 °C) and against concentrated harsh chemicals such as sodium hydroxide, ...

We developed a simple, compact microfluidic device to perform high dynamic-range digital polymerase chain reaction (dPCR) in an array of isolated 36-femtoliter microreactors. The density of the microreactors exceeded 20000/mm(2). This device, made from polydimethylsiloxane (PDMS), allows the samples to be loaded into all microreactors simultaneously. The microreactors are completely sealed thro...

Microreactors consist of tens to hundreds of micrometer-scale channels. The residence time of a fluid can be set exactly and backmixing can be minimized. Particularly, very short residence time can be achieved. In addition, it is possible to precisely control the reaction temperature due to large surface to volume ratio of channels. These features of microreactors make it possible to realize th...

Microreaction technology, which is an interdisciplinary science and engineering area, has been the focus of different fields of research in the past few years. Several microreactors have been developed. Enzymes are a type of catalyst, which are useful in the production of substance in an environmentally friendly way, and they also have high potential for analytical applications. However, not ma...

This paper presents a two-dimensional-in-space mathematical model of biosensors based on an array of enzyme microreactors immobilised on a single electrode. The modeling system acts under amperometric conditions. The microreactors were modeled by particles and by strips. The model is based on the diffusion equations containing a nonlinear term related to the Michaelis-Menten kinetics of the enz...

We introduce a novel approach for synthesizing mesoporous hydroxyapatite (HAp, (Ca)10, (PO4)6(OH)2) using double emulsion droplets as microreactors. By using capillary microfluidic techniques, the size and the geometry of the droplet microreactors can be tuned easily. Double emulsion droplets offer the combined advantages of both shielding the reactants and on-demand addition of reactants; this...

This work presents an analysis about microreactors of different geometries for the biodiesel synthesis. The microreactors were made by a polymeric substrate with the photolithography technique. Simulations were made using the computational fluid dynamics software ANSYS-CFX. They show the flow behavior through the microchannels. Experiments were performed to produce biodiesel, with syringe pumps...

Polymeric microreactors have emerged as a new generation of carriers that hold tremendous promise in the areas of cancer therapy, controlled delivery of drugs, for removal of pollutants etc. Present work reports a simple and convenient methodology for synthesis of polystyrene and poly caprolactone microreactors. An aqueous suspension of carboxylated (1μm) polystyrene latex particles was mixed w...

Microreactors fabricated with optically transparent inorganic polymers from two types of ceramic precursors using a UV-micro-imprinting process demonstrated reliable solvent resistance, biocompatible and capability for performing photo catalytic and organic synthetic reactions, which were compared with batch systems and glass based microreactors. It is for the first time that the polymer-based ...

The union between polymer science and microfluidics is reviewed. Fluids in microreactors allow the synthesis of a wide range of polymeric materials with unique properties. We begin by discussing the important fluid dynamics that dominate the behavior of fluids on the micrometer scale. We then progress through a comprehensive analysis of the polymeric materials synthesized to date. This highligh...