The prevalence of oral tumor has exponentially increased in recent years; however, the effective therapies or prevention strategies are not sufficient. Red mold rice is a traditional Chinese food, and several reports have demonstrated that red mold rice had an anti-tumor effect. However, the possible anti-tumor mechanisms of the red mold rice are unclear. In this study, we examined the anti-tum...

Objective(s): The pathophysiology of neurodegenerative diseases is complicated, in which inflammatory reactions play a vital role. Microglia cells activation, an essential process of neuroinflammation, can produce neurotoxic molecules and neurotrophic factors, which aggravate inflammation and neuronal injury. Monascin, a major component of red yeast rice, is an azaphil...

Deep ocean water (DOW) has, in previous studies, been found to be a novel anti-obesity drink and useful in raising Monascus-produced monascin and ankaflavin levels. This may resolve the limited anti-obesity ability of red mold dioscorea (RMD) known as the Monascus purpureus-fermented Disocorea batatas. This study aims to compare the anti-obesity effect of DOW-cultured RMD (DOW-RMD) and ultra-pu...

Taking monascin as the research object, was extracted from red kojic rice by ethanol extraction and with 60%, 70% 80% respectively. Finally, it concluded that when concentration of 70%, rate highest, reached 75.68%. The bacteriostatic experiments extract fermentation showed had strong inhibitory effect on Staphylococcus aureus Bacillus subtilis , weak ability Escherichia coli Aspergillus niger ...

Abstract Angkak is one of the Monascus fermented products with rice as a substrate. In addition, Chinese yam, potatoes, soybean, ginseng and onions can be used substrate for fermentation by sp. It was known that product produces several bioactive compounds have antihyperlipidemic activity. These are monacolin-K pigment (monascin ankaflavin). Each these has different cholesterol inhibitory The p...

A chemical study on the n-BuOH-soluble fraction of the 95% EtOH extract of red yeast rice fermented with the fungus Monascus pilosus BCRC 38093 (Eurotiaceae) has resulted in the isolation of one new natural pyrrole derivative, designated as monascuspyrrole (1) together with nine known compounds, 3β-hydroxystigmast-5-en-7-one (2), β-sitostenone (3), monascin (4), ankaflavin (5), N-trans-feruloyl...

Abstract Monascus pigments (MPs) with different color characteristics, produced by submerged fermentation of purpureus M9, have potential application in food industry. In the present study, effects and regulatory mechanisms ammonium nitrate (AN) on characteristics MPs were investigated. The concentration intracellular was significantly decreased when subjected to AN. hue lightness value indicat...

Hypertension and cardiovascular complications are the leading causes of death worldwide. Antihypertensive drugs often cause various side effects, and improper use of antihypertensive medications can result in irreparable damage. Edible fungi of the Monascus species have been used as traditional Chinese medicines in Southeast Asia for several centuries. The fermented products of Monascus purpure...

Deep ocean water (DOW) obtained from a depth of more than 200 m includes abundant nutrients and minerals. DOW was proven to positively increase monascin (MS) and ankaflavin (AK) production and the anti-adipogenesis effect of Monascus-fermented red mold dioscorea (RMD). However, the influences that the major metals in DOW have on Monascus secondary metabolite biosynthesis and anti-adipogenesis r...