نتایج جستجو برای: N-methyl-D-aspartate

تعداد نتایج: 1509619  

Journal: :caspian journal of neurological sciences 0
ali ghabeli-juibary resident of neurology, department of neurology, student research committee, school of medicine, mashhad university of medical sciences, mashhad, iran amir rezaei-ardani assistant professor of psychiatry, psychiatry and behavioral sciences research center, mashhad university of medical sciences, mashhad, iran fariborz rezaeitalab assistant professor of neurology, department of neurology, school of medicine, mashhad university of medical sciences, mashhad, iran ; [email protected] mahdieh verdipoor resident of neurology, department of neurology, student research committee, school of medicine, mashhad university of medical sciences, mashhad, iran

anti-n-methyl-d-aspartate-receptor (nmda-r) encephalitis is a new autoimmune disorder, often paraneoplastic in nature, presenting with complex neuropsychiatric symptoms. diagnosed serologically, this disorder is often responsive to immunosuppressant treatment. we here in report the case of a 56-year-old man with anti nmda-r encephalitis presenting initially with disorientation and hallucination...

Journal: :iranian journal of basic medical sciences 0
jalal solati department of biology, faculty of science, karaj islamic azad university, karaj, iran ramin hajikhani department of veterinary medicine, karaj islamic azad university, karaj, iran

objective(s) the central nucleus of the amygdala (cea) is a forebrain structure which is important in regulation of ingestive behavior and there is direct and circumstantial evidence to indicate that some circuits involved with feeding behavior include glutamatergic elements. the present study examined whether administration of nma (n-methyl-dl-aspartic acid) or mk801 into the cea altered water...

Background Anti-N-methyl- d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune neurological disorder that usually occurs as a paraneoplastic syndrome and is particularly associated with ovarian teratoma. Standard therapy for severe cases is not established and the prognosis in patients who do not respond to first-line treatment is poor. Case Report An 11-year-old boy complained ps...

ژورنال: :مجله دانشکده پزشکی اصفهان 0
صمد جوادی دانشجوی دکتری، گروه زیست شناسی، دانشکده علوم، واحد علوم و تحقیقات فارس، دانشگاه آزاد اسلامی و گروه زیست شناسی، دانشکده علوم، واحد شیراز، دانشگاه آزاد اسلامی، شیراز، ایران حجت اله علایی استاد، گروه فیزیولوژی، دانشکده ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران سیدابراهیم حسینی دانشیار، گروه زیست شناسی، دانشکده ی علوم، دانشگاه آزاد اسلامی واحد شیراز، شیراز، ایران محمدامین عدالت منش دانشیار، گروه زیست شناسی، دانشکده ی علوم، دانشگاه آزاد اسلامی واحد شیراز، شیراز، ایران مریم راداحمدی استادیار، گروه فیزیولوژی، دانشکده ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

مقدمه: اعتیاد، اختلال مغزی همراه با تغییرات نوروبیولوژیک است. کورتکس پره فرونتال در حافظه، یادگیری، پاداش و اعتیاد نقش دارد. این مطالعه، با هدف بررسی اثر تزریق 2-amino-5-phosphopentanoic acid (ap5)، آنتاگونیست گیرنده ی گلوتامات، در ناحیه ی پره فرونتال بر تمایل به مورفین انجام شد. روش ها: در مجموع، از 27 گروه موش صحرایی نر نژاد ویستار (6 = n) استفاده شد. بدین منظور، از 7 گروه آزمایشی جهت تعیین د...

2013
Yan Li Silvia Sacchi Loredano Pollegioni Alo C. Basu Joseph T. Coyle Vadim Y. Bolshakov

Mechanisms of N-methyl-D-aspartate receptor-dependent synaptic plasticity contribute to the acquisition and retention of conditioned fear memory. However, synaptic rules which may determine the extent of N-methyl-D-aspartate receptor activation in the amygdala, a key structure implicated in fear learning, remain unknown. Here we show that the identity of the N-methyl-D-aspartate receptor glycin...

Journal: :anesthesiology and pain medicine 0
manzumeh-shamsi meymandi neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, iran fariborz keyhanfar pharmacology department, iran university of medical sciences, tehran, iran; pharmacology department, iran university of medical sciences, tehran, iran. tel: +98-2188058696, fax: +98-2188052978 omid yazdanpanah neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, iran gioia heravi neuroscience research center, institute of neuropharmacology, kerman university of medical sciences, kerman, iran

conclusions our findings support the role of nmdars in pregabalin antinociception, because the nmdar agonist, unlike the antagonist, decreased the antinociceptive effect of pregabalin, even if tail flick is not an adequate pain assessment method in this regard. background pregabalin as a new anticonvulsant has been used in different pain treatments. objectives the aim of this study was to inves...

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