Nipple-sparing mastectomy (NSM) is an increasingly utilized surgical option in managing breast carcinoma; however, data on malignant involvement of a separately submitted nipple margin are scant. Consecutive NSM, including those performed for therapeutic and prophylactic purposes, over a 4-year period (2007-2011), were studied. A separately submitted nipple margin was evaluated by permanent H&E...

BACKGROUND Ischemic complications after nipple-sparing mastectomy (NSM) have been associated with numerous variables. However, the impact of NSM flap thickness has been incompletely evaluated. METHODS NSM flap thickness was determined for all NSMs from 2006 to 2016 with available pre- or postoperative breast magnetic resonance imaging (MRIs). Demographics and outcomes were stratified by those...

this study was conducted to investigate the effects of dietary nigella sativa meal (nsm) on the growth performance, blood parameters, carcass characteristics, egg yolk cholesterol and meat quality in japanese quail. for this purpose 300 one-day old japanese quail chicks in a completely randomized design was used with five treatments in four replicates )containing 15 birds each(. the experimenta...

PURPOSE This study aimed to investigate the incidence of nodal skip metastasis (NSM) to identify the risk factors that influence NSM and to assess the prognostic value of NSM in patients with thoracic esophageal squamous cell carcinoma (ESCC). PATIENTS AND METHODS Between January 2009 and December 2013, 285 patients with ESCC with positive lymph nodes who underwent complete resection were enr...

The nonstructural NSm protein of tomato spotted wilt tospovirus (TSWV) represents a putative viral movement protein involved in cell-to-cell movement of nonenveloped ribonucleocapsid structures. To study the molecular basis of NSm function, we expressed the protein in Escherichia coli and investigated protein-protein and protein-RNA interactions of NSm protein in vitro. NSm specifically interac...

FGSS118 Reproduction in the 21st Century This course will cover basic human reproductive biology, new and future reproductive and contraceptive technologies, and the ethics raised by reproductive issues. Offering: Crosslisting Grading: A-F Credits: 1.00 Gen Ed Area: NSM-BIOL, NSM-BIOL, NSM-BIOL, NSM-BIOL, NSM-BIOL Identical With: BIOL118, PHIL118, SISP118, BIOL118, PHIL118, BIOL118, PHIL118, BI...

The M genome segment of Bunyamwera virus (BUNV)-the prototype of both the Bunyaviridae family and the Orthobunyavirus genus-encodes the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural glycoproteins, Gn and Gc, and a nonstructural protein, NSm. The cleavage mechanism of orthobunyavirus GPCs and the host proteases involved have not been clarified. In thi...

OBJECTIVE To evaluate the oncologic safety of nipple-sparing mastectomy (NSM) for breast cancer patients based on current literature. DATA SOURCES A comprehensive literature search of Medline, Embase databases was conducted for studies published through March 2014. STUDY SELECTION Our search criteria included English-language studies that focused on NSM at nipple-areola complex (NAC) involv...

The movement protein NSm of Tomato spotted wilt tospovirus (TSWV) plays pivotal roles in viral intercellular trafficking. Recently, the TSWV NSm was also identified as an avirulence (Avr) determinant during the Sw-5b-mediated hypersensitive response (HR). However, whether the cell-to-cell movement of NSm is coupled to its function in HR induction remains obscure. Here, we showed that the NSm mu...

Nipple-sparing mastectomy (NSM) is the latest advancement in the treatment of breast cancer, which permits complete preservation of the nipple-areola complex (NAC). Recent studies suggest similar recurrence rates with NSM compared with traditional mastectomy techniques.1–6 Moreover, NSM has been demonstrated in multiple studies to be a safe and effective procedure from a reconstructive perspect...