The effect of 100 mg of ethanol extract of Nardostachys jatamansi was studied on the mice exposed to 6 Gy electron beam radiation. Treatment of mice with 100 mg of Nardostachys jatamansi extract for 15 days before irradiation reduced the symptoms of radiation sickness when compared with the nondrug treated irradiated groups. The irradiation of animals resulted in an elevation in lipid peroxidat...

An aqueous root extract from Nardostachys jatamansi was investigated for its antioxidant and anticataleptic effects in the haloperidol-induced catalepsy rat model of the disease by measuring various behavioral and biochemical parameters. Catalepsy was induced by administration of haloperidol (1 mg/kg, ip) in male albino rats. A significant (P < 0.01) reduction in the cataleptic scores were obse...

The plant Nardostachys jatamansi DC. (Valerianaceae) is a critically endangered rhizome bearing medicinal herb. It is restricted to specialized habitats in high altitudes of Himalaya ranging from 3000 to 5000m. Nardostachys jatamansi has been traditionally employed in treatment of wide range of disorders including nervous system, digestive system, circulatory system, respiratory system, urinary...

The present study explores the hepatoprotective activity of various extracts of Ferula asafoetida, Momordica charantia Linn and Nardostachys jatamansi against experimental hepatotoxicity. Polyherbal suspensions were formulated using extracts showing significant activity and evaluated for both physicochemical and hepatoprotective activity in comparison with LIV-52 as standard. Petroleum ether (6...

AIM The present study evaluated the effect of ethanolic extract of Nardostachys jatamansi roots (NJet) on MYCN mediated regulation of expression of MDM2 and p53 proteins in neuroblastoma cell lines, IMR-32 and SK-N-MC. MATERIALS AND METHODS The effect of NJet on cell viability was determined by MTT; and on growth kinetics was evaluated by trypan blue dye exclusion method and soft agar assay. ...

sumbul-ut-teeb (Nardostachys jatamansi) &amp; khulanjan (Alpinia galanga)are extensively used drugs by our ancient Unani physicians for the management of Gastro hepatic diseases due to cold temperament such as gastritis,metabolic disorders, tashhamul kabid (fatty liver)

Nardostachys jatamansi is a well-documented herbal agent used to treat digestive and neuropsychiatric disorders in oriental medicinal systems. However, few simple, rapid, and comprehensive methods were reported for quality assessment and control of N. jatamansi. Herein, a UPLC with photodiode array detection method was developed for both fingerprint investigation of N. jatamansi and simultaneou...

Background and objectives: The cholinergic deficit correlates with the severity of Alzheimer’s disease. The cholinergic function can be improved by AChE inhibitors blocking this key enzyme in the breakdown of acetylcholine. Based on traditional medicine, during two last decades the use of herbal medicinal substances in dementia therapy has been studied. Nardostachys jataman...

Plants have been use for the treatment, mitigation and cure of disease since time immemorial. The natural recourses are considered as safe human use. Ayurveda advocates Jatamansi in various ailments. In present review article we tried to establish morphological, ehno-pharmacological therapeutic aspect Jatamansi. search engines like, Google scholar, EMBASE, pub med, med central used literary inf...