Developing green solvents with low toxicity and cost is an important issue for the biochemical industry. Synthetic ionic liquids and deep eutectic solvents have received considerable attention due to their negligible volatility at room temperature, high solubilization ability, and tunable selectivity. However, the potential toxicity of the synthetic ionic liquids and the solid state at room tem...

The purpose of this study was to investigate the cytotoxic profiles of different ternary natural deep eutectic solvents (NADESs) containing water. For this purpose, five different NADESs were prepared using choline chloride as a salt, alongside five hydrogen bond donors (HBD) namely glucose, fructose, sucrose, glycerol, and malonic acid. Water was added as a tertiary component during the eutect...

In recent years, green solvents named deep eutectic solvents (DESs) have been found to possess significant properties and to be applicable in several technologies. Choline chloride (ChCl) mixed with urea at a ratio of 1:2 and 80 °C was the first discovered DES. In this article, chemical structure and combination mechanism of ChCl: urea based DES were investigated. Moreover, the implementation o...

In the present study results related to the in vivo administration of Natural Deep Eutectic Solvents (NADES)-solubilized berberine are reported for the first time. NADES are mixtures of small natural compounds having a melting point significantly lower than that of any individual component. Such solvents have gained much attention of the scientific community in the green chemistry area, being c...

Natural Deep Eutectic Solvents (NADES) are composed of supramolecular interactions two or more natural compounds, such as organic acids, sugars, and amino they being used a new media alternative to conventional solvents. In this study, application NADES is presented possible technology for biofilm structural breaker in complex systems since the current solvents cleaning extraction components us...

Natural deep eutectic solvents (NADESs) considered as “green” solvents offer an efficient, safe, sustainable, and cost effective method alternative to conventional extraction while microwave assisted extraction (MAE) is a convenient, rapid, environmental friendly and efficient technique. The combination of NADESs with MAE was applied in this study for the recovery of phenolic compounds from oli...