background nephrolithiasis in children is an important cause of morbidity worldwide. the current retrospective study aims at identifying epidemiological characteristics and risk factors of nephrolithiasis among children under 18 years old attending at nephrology clinic of amir kabir hospital of arak, iran, in 2014. methods the current case-control study was conducted among 166 children in 2 equ...

Nephrolithiasis is a common disorder worldwide. E-cadherin (CDH1) is involved in epithelial cell-cell interactions and plays important roles in the etiology of nephrolithiasis. We hypothesized that variants in the CDH1 gene are associated with risk of nephrolithiasis. In a hospital-based case-control study of 127 nephrolithiasis patients and 152 controls frequency matched by age and sex, we gen...

BACKGROUND Nephrolithiasis is a complex, multifactorial disease resulting from genetic and environmental interaction. The pathogenesis of nephrolithiasis is far from being understood. So far, no gene locus for autosomal dominant nephrolithiasis only has been described. We here identified a new suggestive gene locus for autosomal dominant nephrolithiasis by a genome-wide search for linkage in a ...

Nephrolithiasis is a disease common in both the Western and non-Western world. Several population based studies have demonstrated a rising prevalence and incidence of the disease over the last several decades. Recurrence occurs frequently after an initial stone event. The influence of diet on the risk of nephrolithiasis is important, particularly dietary calcium and fluid intake. An increasing ...

BACKGROUND Non-alcoholic fatty liver disease (NAFLD), a hepatic manifestation or precursor of metabolic syndrome, may increase nephrolithiasis, a renal manifestation of insulin resistance, but the prospective association between NAFLD and incident nephrolithiasis has not been evaluated. We examined the association of NAFLD with the development of nephrolithiasis in a large cohort of Korean men ...

PURPOSE Kidney stones (nephrolithiasis) are a widespread disease. Thus, blocking stone formation and finding new therapeutic methods is an important area of study. Diosmin (a major component of the bile) is known to have antioxidant as well as renoprotective effects. The present investigation aimed to evaluate the effect of diosmin on renal tissue protection in rats with ethylene glycol-induced...

INTRODUCTION To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis. METHODS Systematic review and meta-analysis of epidemiological studies. Data sources; MEDLINE, EMBASE and CINAHL databases, hand-searched reference lists, citation history and contact ...

Aims: Nephrolithiasis and nephrocalcinosis are progressive diseases that can lead to renal impairment. The aim of this analysis was to evaluate aetiological factors, metabolic screening, diagnostic algorithm, treatment, prophylactic measures and follow-up in children with nephrolithiasis and nephrocalcinosis. Patients and methods: Retrospective study of 63 children (36 males, 27 females) with n...

Nephrolithiasis is one of the common diseases without effective treatment, incidence which has increased in world recent decades. Sodium-glucose co-transporter 2 inhibitor can reduce probability nephrolithiasis diabetic and non-diabetic people.

AIM To investigate the association of nephrolithiasis and solute carrier family 2, facilitated glucose transporter, member 9 (SLC2A9), also known as glucose transporter type 9, Glut9. METHODS A total of 145 participants were recruited in the period April-October 2008 from the Department of Mineral Research of the Medical School Osijek, Osijek, Croatia; 58 (40%) had confirmed nephrolithiasis a...