In this study, the chemopreventive efficacy of Nigella sativa seed powder as an important chemopreventive herb on the formation of colon tumor has been examined through measuring the levels of hepatic oxidative stress and metabolizing enzymes in 1,2-dimethylhydrazine (DMH)-induced colon cancer in rats. Male Wistar rats were divided into 6 groups as untreated control, Sham, DMH (30mg/kg b.w) rec...

The seeds of Nigella sativa L., commonly known as black seed or black cumin, and its extracts are used in folk medicine in the Middle East and in Asian countries for the promotion of good health and as a remedy for many ailments. These seeds have many acclaimed medicinal properties such as broncho-dilatory, immunopotentiating, analgesic, anti-inflammatory, and hypotensive. In the present study,...

Black Seed The date and location of domestication of Nigella sativa is not clearly established, but the plant was certainly under wide cultivation more than 3000 years ago, when it was placed in the tomb of Egyptian King Tutankhamun. Historical evidence also shows contemporaneous, or earlier, black seed cultivation in Jordan and Iraq. In addition, wild types of Nigella sativa grow in Turkey, Sy...

OBJECTIVE Nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. Numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. The aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of Nigella sativa oil in patients with rheumatoid arth...

Many studies have shown that naturally occurring compounds may support prevention and treatment of various diseases, including cancer. Pharmacological investigations revealed a wide spectrum of Nigella sativa biological activities. Combining natural compounds together with synthetic drugs may increase the anticancer activity and limit severe side effects of such a treatment and may be an altern...

Many studied were conducted to evaluate the antihepatotoxic and antioxidant activities of Silybum marianum and proved these actions. The Naturally grown seed in Iraqi-Kurdistan Region also were studied for its chemical contents and biological activities. Vegetable oils occur in various plant parts mainly concentrated in the seeds. In this study comparison was made between the fatty acid pattern...

OBJECTIVE Oxidative stress plays an important role in the etiology of diabetic complications. Diabetes impairs hippocampus neurogenesis, synaptic plasticity, and learning. The aim of this study was to investigate the effects of hydroalcoholic extract of Nigella sativa seed on oxidative stress in STZ-induced diabetic rats' hippocampus. MATERIALS AND METHODS Diabetes induced by 60 mg/kg STZ, i....

to study the effect of salinity stress on seed germination and seedling growth of four medicinal plants, nigella sativa l., cannabis sativa l., trigonella foenum graecum and cynara scolymus l. an experiment was conducted in the botany laboratory of islamic azad university, birjand branch. a completely randomized design (crd) with 3 replications was used as separately for each species. treatment...

Nigella sativa (black seed) is an important medicinal herb. In many Arabian, Asian and African countries, black seed oil is used as a natural remedy for a wide range of diseases, including various allergies. The plant's mechanism of action is still largely unknown. Due to the lack of study data on its efficacy in allergies, four studies on the clinical efficacy of Nigella sativa in allergic dis...

OBJECTIVE To determine the analgesic effect of ethanolic extract of Nigella sativa seeds on experimentally-induced pain in albino mice. STUDY DESIGN Randomized controlled trial (RCT). PLACE AND DURATION OF STUDY Physiology Department, Services Institute of Medical Sciences (SIMS), Lahore, from May to September, 2009. METHODOLOGY The study was carried out in 90 male albino mice using aceti...