Recently, a novel ninhydrin reaction with cyanide has opened new ways to detect this poison in the body fluids and the environmental samples. Mainly, detection of cyanide with ninhydrin at a crime scene could be of prime interest for forensic investigators. Besides, the reaction conditions are very common, except the need to avoid oxygen and oxidizers. The ninhydrin-based assay proved to be hig...

      Dendrimer based nanostructures have been increasingly used for delivery of drugs/genes. These nanosystems, as non-viral gene delivery systems, were shown to have relatively high transfection efficiency despite exerting somewhat cytotoxicity. In this current investigation, poly(amido amine) (PAMAM) dendrimers, generation  (G) zero to five, PEGylated PAMAM G3 and a new quaternized PAMAM G4 ...

dendrimer based nanostructures have been increasingly used for delivery of drugs/genes. these nanosystems, as non-viral gene delivery systems, were shown to have relatively high transfection efficiency despite exerting somewhat cytotoxicity. in this current investigation, poly(amido amine) (pamam) dendrimers, generation  (g) zero to five, pegylated pamam g3 and a new quaternized pamam g4 were s...

ABSTRACT. One-pot, mild and efficient synthesis of various spiro-nitrogen heterocycle compounds, based on the reaction ninhydrin 1,2-diamino-benzene, (indenoquinoxalin), with N-heterocycle compounds dialkylacetylenedicarboxylates is described. Using this approach, at a temperature 50-60 °C in acetonitrile solvent, can be obtained very high yields.
 
 KEY WORDS: Ninhydrin, 1,2-Diaminob...