نتایج جستجو برای: Nonobstructive

تعداد نتایج: 833  

2011
Claudia P Rojas Arnel K Urbiztondo Jocelyn H Bruce Maria M Rodriguez

Etiology of multicystic dysplastic kidney (MCDK) remains unknown. Not all cases are associated with obstruction. We compared by immunohistochemistry 17 cases of MCDK (10 cases with and seven without obstruction) to 17 controls and 20 fetal kidneys. TGF-β was negative in obstructive MCDKs and positive in nonobstructive MCDK. IGF2 was overexpressed in obstructive and underexpressed in nonobstruct...

Journal: :Clinical cardiology 2010
Vijay S Ramanath David F Armstrong Mary Grzybowski Sahand Rahnama-Mohagdam Umesh U Tamhane Kelly Gordon James B Froehlich Kim A Eagle Elizabeth A Jackson

BACKGROUND Management of acute coronary syndrome (ACS) patients with nonobstructive epicardial coronary artery disease (CAD) remains poorly understood. HYPOTHESIS Acute coronary syndrome patients with nonobstructive CAD are less likely to receive effective cardiac medications upon discharge from the hospital. METHODS We identified patients hospitalized with ACS that underwent coronary angio...

Journal: :JACC. Cardiovascular imaging 2017
Hamed Emami Richard A P Takx Thomas Mayrhofer Sumbal Janjua Jakob Park Amit Pursnani Ahmed Tawakol Michael T Lu Maros Ferencik Udo Hoffmann

OBJECTIVES This study sought to determine prognostic value of nonobstructive coronary artery disease (CAD) for atherosclerotic cardiovascular disease (ASCVD) events and to determine whether incorporation of this information into the pooled cohort equation reclassifies recommendations for statin therapy as defined by the 2013 guidelines for cholesterol management of the American College of Cardi...

2016
Fang-Yang Huang Bao-Tao Huang Wen-Yu Lv Wei Liu Yong Peng Tian-Li Xia Peng-Ju Wang Zhi-Liang Zuo Rui-Shuang Liu Chen Zhang Yi-Yue Gui Yan-Biao Liao Mao Chen Ye Zhu

Limited data exist regarding the outcomes of patients with nonobstructive coronary artery disease (CAD) detected by computed tomography coronary angiography (CTCA) or invasive coronary angiography (ICA). Our aim was to compare the prognosis of patients with nonobstructive coronary artery plaques with that of patients with entirely normal arteries. The MEDLINE, Cochrane Library, and Embase datab...

Journal: :The American journal of cardiology 2013
Roy Beigel Sella Brosh Orly Goitein Einat Guttman Ilia Novikov Amit Segev Yariv Gerber Dan Oieru Eli Konen Hanoch Hod Shlomi Matetzky

Coronary computed tomographic angiography can detect nonobstructive atherosclerotic lesions that would not otherwise have been detected with functional cardiac imaging. Currently, limited data exist regarding the clinical significance of these lesions in patients with acute chest pain. The aim of our study was to examine the prognostic significance of these nonobstructive findings in a patient ...

Journal: :Circulation. Cardiovascular quality and outcomes 2010
Thomas M Maddox P Michael Ho Matthew Roe David Dai Thomas T Tsai John S Rumsfeld

BACKGROUND Secondary prevention therapies are indicated for patients with coronary artery disease (CAD). However, patients with nonobstructive CAD may be less likely to receive these therapies compared with patients with obstructive CAD. Therefore, we compared rates of secondary prevention medication prescription between patients with nonobstructive and obstructive CAD. METHODS AND RESULTS We...

Journal: :Physiological genomics 2016
Liming Weng Kent D Taylor Yii-Der Ida Chen George Sopko Sheryl F Kelsey C Noel Bairey Merz Carl J Pepine Virginia M Miller Jerome I Rotter Martha Gulati Mark O Goodarzi Rhonda M Cooper-DeHoff

Nonobstructive coronary artery disease (CAD) in women is associated with adverse cardiovascular (CV) outcomes; however, information regarding genetic variants that predispose women to nonobstructive CAD is lacking. Women from the Women's Ischemia Syndrome Evaluation (WISE) Study and the St. James Women Take Heart (WTH) Study were genotyped with the Cardio-MetaboChip. WISE enrolled women with sy...

Journal: :Circulation. Cardiovascular imaging 2014
Marcio Sommer Bittencourt Edward Hulten Brian Ghoshhajra Daniel O'Leary Mitalee P Christman Philip Montana Quynh A Truong Michael Steigner Venkatesh L Murthy Frank J Rybicki Khurram Nasir Luis Henrique W Gowdak Jon Hainer Thomas J Brady Marcelo F Di Carli Udo Hoffmann Suhny Abbara Ron Blankstein

BACKGROUND The contribution of plaque extent to predict cardiovascular events among patients with nonobstructive and obstructive coronary artery disease (CAD) is not well defined. Our objective was to evaluate the prognostic value of plaque extent detected by coronary computed tomography angiography. METHODS AND RESULTS All consecutive patients without prior CAD referred for coronary computed...

Journal: :Journal of the American College of Cardiology 2011
Fay Y Lin Leslee J Shaw Allison M Dunning Troy M Labounty Jin-Ho Choi Jonathan W Weinsaft Sunaina Koduru Millie J Gomez Augustin J Delago Tracy Q Callister Daniel S Berman James K Min

OBJECTIVES We examined mortality risk in relation to extent and composition of nonobstructive plaques by 64-detector row coronary computed tomographic angiography (CCTA). BACKGROUND The prognostic significance of nonobstructive coronary artery plaques by CCTA is poorly understood. METHODS We prospectively evaluated consecutive adults from 2 centers undergoing 64-detector row CCTA without pr...

Journal: :Molecular & cellular proteomics : MCP 2011
Andrei P Drabovich Keith Jarvi Eleftherios P Diamandis

Seminal plasma is a promising biological fluid to use for noninvasive clinical diagnostics of male reproductive system disorders. To verify a list of prospective male infertility biomarkers, we developed a multiplex selected reaction monitoring assay and measured the relative abundance of 31 proteins in 30 seminal plasma samples from normal, nonobstructive azoospermia and post-vasectomy individ...

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