نتایج جستجو برای: Odonthobuthus doriae

تعداد نتایج: 88  

Journal: :Journal of Venomous Animals and Toxins including Tropical Diseases 2006

Journal: :iranian journal of pharmaceutical research 0
a jalali z hossininasab z ehsani aa zare afshin zarghi h vatanpour

the effect of odonthobuthos doriae (o.d) scorpion venom at 0/3, 1 and 3, 10 µg/ml concentrations were investigated on nerve-muscle transmission, using the twitch tension technique. a concentration of 0.3 µg/ml caused a small change in the twitch height in response to indirect muscle stimulation, but higher concentrations (1, 3, 10 µg/ml) caused a transient augmentation in twitch response follow...

Journal: :Molecular pharmacology 2006
Chantal Maertens Eva Cuypers Mehriar Amininasab Amir Jalali Hossein Vatanpour Jan Tytgat

Voltage-gated sodium channels are essential for the propagation of action potentials in nociceptive neurons. Nav1.7 is found in peripheral sensory and sympathetic neurons and involved in short-term and inflammatory pain. Nav1.8 and Nav1.3 are major players in nociception and neuropathic pain, respectively. In our effort to identify isoform-specific and high-affinity ligands for these channels, ...

2017
Sainaz Ghasemi Amir Ahmad Salarian Abbas Zare Mirakabadi Somayeh Jafarinejad Mahmoud Ghazi-Khansari

Scorpion venom toxicity is one of the major medical concerns from old years, due to its influence on human activities and health. From many years ago a lot of researches established to examine different aspects of venom toxicity and its effects on different organs. During these years researchers are doing more specific studies on the cytotoxicity of scorpion venom. In Iran, Odonthobuthus doriae...

2017
Rouhullah Dehghani Hamid Kassiri

Background Scorpions are among the world's venomous arthropods, they sting humans every year, suffering painful symptoms or losing their lives because of the venom. Odontobuthus doriae Thorell 1876 (Arachnida: Scorpionida: Buthidae) is a scorpion of medical importance and therefore its geographical distribution in Isfahan Province has been studied. Methods This descriptive cross-sectional stu...

Journal: :Toxicon : official journal of the International Society on Toxinology 2007
A Jalali H Vatanpour Z Hosseininasab E G Rowan A L Harvey

The yellow Iranian scorpion Odontobuthus doriae can cause fatal envenoming, but its mechanism of action is unclear. One of the reported manifestations of envenoming is moderate to severe involuntary tremor of skeletal muscle. In order to understand better the mechanism of action of this venom on skeletal muscle function, we examined the effects of the venom in vitro on chick biventer cervicis (...

Scorpion venom toxicity is one of the major medical concerns from old years, due to its influence on human activities and health. From many years ago a lot of researches established to examine different aspects of venom toxicity and its effects on different organs. During these years researchers are doing more specific studies on the cytotoxicity of scorpion venom. In Iran, Odonthobuthus doriae...

Scorpion venom toxicity is one of the major medical concerns from old years, due to its influence on human activities and health. From many years ago a lot of researches established to examine different aspects of venom toxicity and its effects on different organs. During these years researchers are doing more specific studies on the cytotoxicity of scorpion venom. In Iran, Odonthobuthus doriae...

2012
Amir Ahmad Salarian Amir Jalali Abbas Zare Mirakabadi Hossein Vatanpour Farshad H. Shirazi

Scorpion venom toxicity is of major concern due to its influence on human activities and public health. We investigated the in-vitro process of cell death caused by two Iranian scorpions Odontobuthus doriae and Bothutus salceyi venom on human cell lines. The aim of this study was to provide further information about triggering cell death and suggestion of methods for the elimination of unwanted...

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