We examined complexes between cucurbit[6]uril and each of ortho-, meta-, and para-phenylenediamine using computational methods, Fourier transform ion cyclotron resonance mass spectrometry, and ion mobility spectrometry. These fundamental gas phase studies show that the lowest energy binding sites for ortho- and meta-phenylenediamine are on the exterior of cucurbit[6]uril, whereas para-phenylene...

There is an association between occupational exposure to hair dyes and incidence of cancers. Permanent oxidant hair dyes are consisted of many chemical components including ortho-phenylenediamines. To clarify the mechanism of carcinogenesis by hair dyes, we examined DNA damage induced by mutagenic ortho-phenylenediamine (o-PD) and its derivatives, 4-chloro-ortho-phenylenediamine (Cl-PD) and 4-n...

a simple and facile method for the preparation offe2+ supported on hydroxyapatite-core-shell-γ-fe2o3 nanoparticles (γ-fe2o3@hap-fe2+ nps) as an environmentally friendly and recyclable green catalyst is described and used for the one-pot synthesis of benzimidazoles and benzoxazole derivatives via reactions between aromatic aldehydes and ortho‐phenylenediamine or ortho‐aminophenol in aqueous medi...

Experimental Reagents and chemicals m-Phenylenediamine (mPDA >99%) was purchased from Acros Organics, ethylenediamine (EDA, Sigma Ultra) was obtained from Sigma Aldrich. ortho-Phosphoric acid (85%, ACS certified) was purchased from Fisher Scientific. All the other chemicals were of analytical grade. Buffer solutions with different pH were prepared using chemicals (such as sulphuric acid, citric...

The ability of the electron transport particulate fraction of Azotobacter vinelandii strain O to oxidize tetramethyl-p-phenylenediamine (TMPD) and p-phenylenediamine (PPD) was examined in detail. The highest specific activity for TMPD and PPD oxidation concentrated in the A. vinelandii O R(3) fraction. The A. vinelandii O R(3) fraction was used to develop a standard manometric assay which gave ...

Aromatic amines represent a category of classical environmental hazards which require biotransformation in order to exert their mutagenic and carcinogenic effects. The mutagenic activity of several aromatic amines was tested by means of the w/w+ somatic assay of Drosophila melanogaster employing a wild-type strain Leiden Standard (LS) and an insecticide-resistant stock Hikone-R (HK-R). Four mon...