introduction: myocardial infarction (mi) is associated with increased oxidative stress and reduced antioxidants. some studies have shown that exercise training increases the serum level antioxidants. therefore, this study investigated the effect of rehabilitation training on antioxidant status in patients with myocardial infarction. materials and methods: in this study, 20 patients with myocard...

The colonic lumen is likely to contain oxidants derived from unabsorbed dietary materials including transition metals, rancid fat, drugs and bacterial metabolites. The present study looks at the effect of luminal exposure of different oxidants on colonic mucosal lipid peroxidation and absorptive function. All the oxidants tested induced fluid and electrolyte secretion and indomethacin, a prosta...

Sudden cardiac death (SCD) refers to death after an unexpected sudden cardiac arrest in a patient with or without known structural heart disease. The incidence of SCD in the United States ranges from 300 000 to 460 000 events per year, depending on the criteria for SCD used for surveillance. SCD results from a complex interaction between preexisting cardiac substrates, either structural or gene...

The free radical theory of aging postulates that the production of intracellular reactive oxygen species is the major determinant of life span. Numerous cell culture, invertebrate, and mammalian models exist that lend support to this half-century-old hypothesis. Here we review the evidence that both supports and conflicts with the free radical theory and examine the growing link between mitocho...