monascus purpureus is a fungus that had been cultured on the rice in eastern asian countries since thousands years ago and used as a food for long years. the fungus produces very valuable metabolites with polyketide structure. the most important metabolite is monacolin k, lovastatin or competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase (an affective enzyme in cholesterol s...

A scale-up design procedure, based on a new physical mass transfer (PMT) model, whichdescribes the performance, for aerobic rotating biological contactors (RBC’s) is developed. This scale-up procedure can be used to determine the disc surface area needed to prevent an oxygen limitation or to obtain a specific degree of treatment. In contrast to the empirical, and most previous RBC performance m...

An empirical correlation, based on conventional forms, has been developed to represent the oxygen mass transfer coefficient as a function of operating conditions and organic fraction in two-phase, aqueous-organic dispersions. Such dispersions are characteristic of two-phase partitioning bioreactors, which have found increasing application for the biodegradation of toxic substrates. In this work...

The aim of this work was to investigate the effect of oxygen limitation on whole­ cell oxygenases, and to determine how the physiochemical properties of oils affect their ability to enhance the oxygen transfer rate. Whole-cell oxygenase biocatalysts require oxygen as a substrate for the reaction and for the electron transport chain. The productivity of these bioconversions is therefore influenc...

recently, the production of biosurfactants in bioreactors and their use in various pharmaceutical,chemical and food industries have been developed. optimum production is directly related to the physicochemicalcondition of culture medium (such as ph and temperature) and engineering parameters of bioreactors (such asaeration rate, volume of operation and the amount of energy input). understanding...

recently, the production of biosurfactants in bioreactors and their use in various pharmaceutical,chemical and food industries have been developed. optimum production is directly related to the physicochemicalcondition of culture medium (such as ph and temperature) and engineering parameters of bioreactors (such asaeration rate, volume of operation and the amount of energy input). understanding...