The authors have studied the security management architecture for Personal Networks (PN). The main feature of the proposed architecture is to exploit a trusted cellular system, namely, an IMS (IP Multimedia Subsystem), to provide security functions for PNs over open networks like the Internet. They also proposed two security functions to solve security issues for a PN, PE ID and Key Assignment ...

BACKGROUND Development is ongoing to increase the serotype coverage of pneumococcal conjugate vaccines. We report here the immunogenicity and safety of a new 11-valent pneumococcal conjugate vaccine (Pn-PD) in infants. METHODS In a randomized, single blind study, 154 Finnish infants received 1 of 3 regimens: 4 doses of Pn-PD at 2, 4, 6 and 12-15 months; 3 doses of the Pn-PD at 2, 4 and 6 mont...

BACKGROUND Recent studies suggest an increased frequency of peripheral neuropathy (PN) in Parkinson's disease patients (PD) (Toth et al. 2010). The aim of our study is to verify the increased frequency of PN in our group of PD patients compared to an age-matched control group. We sorted patients according to the duration of L-DOPA treatment, L-DOPA dosage, and age below or over 50 years. METH...

The programmed cell death-1(PD-1)/PD-ligand 1 (PD-L1) pathway is critical to immune homeostasis by promoting regulatory T (Treg) development and inhibiting effector T (such as Th17) cell responses. However, the association between the PD-1/PD-L1 pathway and the Treg/Th17 imbalance has not been fully investigated in pre-eclampsia (PE). In this study, we observed an inverse correlation between th...

BACKGROUND Recent studies have reported that peripheral neuropathy (PN) is common in patients with Parkinson's disease (PD) and raised the possibility that levodopa neurotoxicity is the main culprit. METHODS We evaluated the presence of large & small (autonomic) fiber PN in 54 consecutive patients with PD or parkinsonism in a tertiary outpatient clinic from Brazil. Initial PN screening consis...

A variety of Pd(II) complexes containing the neutral N,P,N-ligand bis(2-picolyl)phenylphosphine (N(py)PN(py)) have been synthesised and characterized by IR and NMR spectroscopy and X-ray diffraction. The neutral complex [PdCl(2)(N(py)PN(py)-N,P)] (1) has been selectively obtained in high yield by reaction of [PdCl(2)(NCPh)(2)] with the ligand in dichloromethane. The cationic complexes [PdCl(N(p...

BACKGROUND Laryngoscopy and intubation increases blood pressure and heart rate. OBJECTIVE The study aims to investigate the effect and safety of gabapentin, esmolol or their combination on the haemodynamic response to laryngoscopy and intubation. METHODS A total of 72 patients undergoing elective surgery were randomly allocated to one of the four groups. First study drug was administered or...

The extensive analysis of the impact of segmental aneuploidy by Lindsley et al. (1972) showed that there are relatively few haplo-lethal loci in the genome and that, with one exception, all loci are triplo-viable. The exceptional locus, which lies in salivary gland chromosome region 83D-E, is associated with lethality when present in either one or three doses in an otherwise diploid individual ...