Primary ovarian insufficiency (POI) can be a devastating disease impacting women below the age of forty. This involves a major decrease in the amount and quality of oocytes, or ovarian reserve in a woman. The distribution of single-nucleotide polymorphisms, rs10407022 and rs3741664, in Iraqi people and its association with primary ovarian insufficiency is the main objective of this study. The m...

BACKGROUND The FMR1 premutation is associated with overt primary ovarian insufficiency (POI). However, its prevalence in women with occult POI (i.e. menstrual cycles, but impaired ovarian response) has not been examined. We hypothesized that both the FMR1 premutation and intermediate allele is more frequent in infertile women with occult POI than in controls, and that a repeat length cutoff mig...

BACKGROUND The clinical impact of postoperative ileus (POI) after colectomy is difficult to quantify financially because of administrative coding limitations. Accurate data are important to allow pharmaco-economic analysis of methods aimed at reducing POI. The aim of this study was to assess the financial impact of POI for the 30-day episode of care for colectomy. STUDY DESIGN We reviewed all...

Successive point-of-interest (POI) recommendation in location-based social networks (LBSNs) becomes a significant task since it helps users to navigate a number of candidate POIs and provides the best POI recommendations based on users’ most recent check-in knowledge. However, all existing methods for successive POI recommendation only focus on modeling the correlation between POIs based on use...

POI, or Points of Interest, refer to the geo-position points in maps. POI provided by Baidu Maps come from different sources. To assure the quality of POI, Baidu checked the validity of every POI and merged them into a standardized dataset. By comparing names and spatial coordinates of POI, calculating similarities and hashing, Baidu built its own POI dataset with a precision higher than 95%. A...

Primary ovarian insufficiency (POI) is a genetically heterogeneous disorder that occurs in familial or sporadic fashion. Through whole exome sequencing in a Chinese pedigree with POI, we identified a novel homozygous missense mutation (ENST00000375755: c.1459G > T, p.D487Y) in the MSH5 gene in two sisters with POI. The homologous mutation in mice resulted in atrophic ovaries without oocytes, an...

pain, nausea, vomiting, and the inability to advance the diet during the postoperative period. Complications of POI include atelectasis and pneumonia. If POI is prolonged, poor wound healing can result, in part, from nutritional deficits. Although the duration of POI is partially dependent on the extent of surgical manipulation, the surgical site, and patient characteristics, a delay in return ...

CONTEXT Idiopathic primary ovarian insufficiency (POI) is a major cause of amenorrhea and infertility. POI affects 1% of women before age 40 years, and several genetic causes have been reported. To date, POI has been considered a monogenic disorder. OBJECTIVE The aim of this study was to identify novel gene variations and to investigate if individuals with POI harbor mutation in multiple loci...

OBJECTIVES A significant number of individuals have high serum follicle stimulating hormone (FSH) levels but do not meet the criteria for diagnosis of premature ovarian insufficiency (POI) due to ongoing menstruation. We compared a group of women with elevated FSH levels and POI with a control group in terms of biochemical markers. METHODS In this cross-sectional retrospective study, 38 POI c...