P ARAPROTEINS* ARE generally found in the serum in patients suffering from multiple myeloma or Waldenstr#{246}m’s macroglobulinemia. Recently, however, there have been a number of reports on patients in whom paraproteinemia#{176} was found in association with a myeloproliferative disorder such as polycythemia, erythroleukemia, acute myeloblastic and lymphoblastic leukemia, and chronic myelocyti...

Paraproteinemia potentially causes peripheral neuropathy via an unknown underlying pathogenetic mechanism. We report a case of pathologically proven amyloid neuropathy with AL amyloidosis with an IgA kappa light chain, which was initially diagnosed as neuropathy associated with monoclonal gammopathy of undetermined significance. This case indicates that in cases of neuropathy with paraproteinem...

Different peripheral neuropathies are linked to paraproteinemia. Anti-myelin-associated glycoprotein (MAG) neuropathy, immunoglobulin or its fragment deposition in the interstitium, light chain amyloidosis (AL amyloidosis) and paraneoplastic mechanisms that cannot be solely attributed deposition, represented by polyneuropathy, organotypic, three main causes of neuropathy correlated with Nerve c...

The clinical and biological relevance of a paraprotein that newly arises after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in non-myeloma patients is unknown. In this study, the incidence, the course, and the clinical impact of paraproteins found after allo-HSCT were investigated in a cohort of 383 non-myeloma patients. Paraproteinemia after allo-HSCT was more frequent (52/38...

purpose: to present a case of bilateral enlargement of eyelids in 29 year old man with sclromyxedema syndrome. case report: a 29- year- old man was referred to labbafinegad clinic with bilateral enlargment of upper and lower eyelids, and foreign body sensation since 9 year ago. investigating of patients history show renal deasese(hematuria ) since 9 year ago. in systemic examination the patient...

As a plasmaproliferative disorder, multiple myeloma (MM) is not expected to cause IO and actually there are no reports on this condition in MM. In this retrospective study, we evaluated serum iron test results in MM patients at diagnosis in order to find the frequency of IO. Iron overload pattern (IOP) was described as increased transferring saturation (> 45%) in the presence of normal to incre...