Parthenolide

نتایج جستجو برای: Parthenolide

تعداد نتایج: 408 فیلتر نتایج به سال:

Parthenolide Inhibits Tubulin Carboxypeptidase Activity

Journal: :Cancer Research 2007

XavierFonrose, FrédéricAusseil, EmmanuelleSoleilhac, VéroniqueMasson, BrunoDavid, IsabellePouny, Jean-ChristopheCintrat, BernardRousseau, CarolineBarette, GeorgesMassiot, LaurenceLafanechère,

متن کامل

(E)-13-(4-Aminophenyl)parthenolide

2013

Narsimha Reddy Penthala, Venumadhav Janganati, Sean Parkin, Kottayil I. Varughese, Peter A. Crooks,

The title compound, C21H25NO3 [systematic name: (3aS,9aR,10aR,10bS,E)-3-[(E)-4-(4-amino-benzyl-idene)-6,9a-dimethyl-3a,4,5,8,9,9a,10a,10b-octa-hydro-oxireno[2',3':9,10]cyclo-deca-[1,2-b]furan-2(3H)-one] was obtained from the reaction of parthenolide [synonym: 4,5-ep-oxy-germacra-1(10),11(13)-dieno-12,6-lactone] with 4-iodo-aniline under Heck reaction conditions. It was identified as the E-isome...

متن کامل

Parthenolide: suggested drug for COVID-19

Journal: :Russian Journal of Infection and Immunity 2020

M.Nemati, F.Danesh Pouya, E.Roshani Asl, Y.Rami,

متن کامل

Targeting Radioresistant Osteosarcoma Cells With Parthenolide

Journal: :Journal of Cellular Biochemistry 2012

DanielZuch, An-HoaGiang, YuriyShapovalov, EdwardSchwarz, RandyRosier, RegisO'Keefe, Roman A.Eliseev,

متن کامل

Parthenolide inhibits tubulin carboxypeptidase activity.

Journal: :Cancer research 2007

Xavier Fonrose, Frédéric Ausseil, Emmanuelle Soleilhac, Véronique Masson, Bruno David, Isabelle Pouny, Jean-Christophe Cintrat, Bernard Rousseau, Caroline Barette, Georges Massiot, Laurence Lafanechère,

Microtubules are centrally involved in cell division, being the principal components of mitotic spindle. Tubulin, the constituent of microtubules, can be cyclically modified on its alpha-subunit by enzymatic removal of the COOH-terminal tyrosine residue by an ill-defined tubulin carboxypeptidase (TCP) and its readdition by tubulin tyrosine ligase (TTL). We and others have previously shown that ...

متن کامل