in this study, flow field and heat transfer of al2o3-cu/water micropolar hybrid nanofluid is investigated in a permeable channel using the least square method. the channel is encountered to chemical reaction, and a constant magnetic field is also applied. the bottom wall is hot and coolant fluid is injected into the channel from the top wall. the effects of different parameters such as the reyn...

In this study, the least square method is applied to study the laminar flow, heat transfer and microrotation of MgO-Ag/water micropolar hybrid nanofluid in a permeable channel. The bottom wall is hot and coolant fluid is injected into the channel from the top wall. The base fluid in the channel is water and volume fraction of nanoparticle (50% Ag and 50% MgO by volume) is between 0 and 0.02. By...

In this research, a two-dimensional mathematical model using  turbulence model was developed in a rectangular channel with granular permeable bed. Finite volume method was used for numerical solution of governing equations. The equations considered are discretized using Hybrid difference scheme while applying SIMPLE algorithm to correct velocity components in the continuity equation. In the dev...

Calcium channels have been suggested to play a major role in the initiation of a large number of signal transduction processes in higher plant cells. However, molecular components of higher plant Ca2+ channels remain unidentified to date. Calcium channel blockers of the phenylalkylamine family and bepridil specifically inhibit Ca2+ influx into carrot (Daucus carota L.) cells. By using a phenyla...

Ligand-Gated Channel Receptors. When a neurotransmitter molecule binds to a receptor that acts as a ligand-gated ion channel, a channel opens, allowing ions to flow across the membrane (see figure). The flow of positively charged ions into the cell depolarizes the portion of the membrane nearest the channel. Because this situation is favorable to the subsequent generation of an action potential...

Despite the importance of reactive oxygen species (ROS) in plant immunity, stress signaling, and development (Mori and Schroeder, 2004; Gadjev et al., 2006), the molecular identities of Ca-permeable channels responding to ROS have not been established. Here, we propose annexins as candidate channel proteins. Elevation of cytoplasmic free calcium ([Ca2+]cyt) as a regulatory step in plant immunit...

Despite the importance of reactive oxygen species (ROS) in plant immunity, stress signaling, and development (Mori and Schroeder, 2004; Gadjev et al., 2006), the molecular identities of Ca-permeable channels responding to ROS have not been established. Here, we propose annexins as candidate channel proteins. Elevation of cytoplasmic free calcium ([Ca2+]cyt) as a regulatory step in plant immunit...

Protracted elevation in intracellular calcium caused by the activation of the N-methyl-d-aspartate receptor is the main cause of glutamate excitotoxic injury in stroke. However, upon excitotoxic injury, despite the presence of calcium entry antagonists, calcium unexpectedly continues to enter the neuron, causing extended neuronal depolarization and culminating in neuronal death. This phenomenon...