background & objectives: oral submucous fibrosis (osmf) is a condition where excessive deposition of dense collagen fibers occurred in the connective tissue of oral mucosa. an alteration of collagen necessitates an in depth understanding of collagen in oral tissues as no breakthrough studies have been reported. therefore the aim was to correlate the clinical, functional and histopathologica...

BACKGROUND Giant cell fibroma (GCF) is a distinct type of fibroma with characteristic large, stellate mononuclear or multinucleated giant fibroblasts; the stroma of GCF is relatively unexplored. The Picrosirus red polarizing microscopy technique is used to characterize the collagen fibers. The aim of this study was to evaluate the staining properties of collagen fibers in GCF and to correlate i...

The uniqueness of polarization microscopy lies in the use of light beams with controlled states of polarization. With such beams, optical properties such as birefringence, dichroism, and optical activity are detectable, and optical constants are determinable in an exceedingly small sample volume. Since birefringence and dichroism generally reflect the arrangement or properties of material the d...