The operation of many nuclear pressurized water reactors is being extended beyond their design lifetime threshold. From the perspective possible further extension, satisfying safety requirements a priority. Characterization structural integrity reactor pressure vessel (RPV) an important issue as it guiding parameter that influences lifetime. Embrittlement RPV material primarily induced by bomba...

BACKGROUND Vessel dilator, a 37-amino acid peptide hormone synthesized in the heart, enhances urine flow 4- to 12-fold and sodium excretion 3- to 6-fold in healthy humans. The present investigation was designed to determine whether vessel dilator might have similar beneficial effects in persons with congestive heart failure (CHF). METHODS AND RESULTS Vessel dilator (100 ng/kg body weight per ...

When arteries are excised, they collapse and shorten spontaneously, which can result in damage to the endothelium. To determine if an intact endothelial cell layer could be preserved in excised vessels, we isolated and cannulated rat carotid artery segments (in situ length, In,, 10-20 mm) at both ends while maintaining both transmural pressure (70 mm Hg) and Li, while maintaining either transmu...

Background: The interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries.Objective: To understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from CT...