Myocardial ischemia is transmurally heterogeneous where the subendocardium is at higher risk. Stenosis induces reduced perfusion pressure, blood flow redistribution away from the subendocardium, and consequent subendocardial vulnerability. We propose that the flow redistribution stems from the higher compliance of the subendocardial vasculature. This new paradigm was tested using network flow s...

Pressure vessels are used for various industrial applications. To ensure safe operation of pressure vessels, it is important to know its burst pressure. Burst pressure is the pressure at which vessel burst/crack and internal fluid leaks. For light weight application pressure vessel are made of composite material. Payload performance /speed /operating range depends up on weight. Use of composite...

In this article fluid-structure interaction of vibrating composite piezoelectric plates is investigated. Since the plate is assumed to be moderately thick, rotary inertia effects and transverse shear deformation effects are deliberated by applying exponential shear deformation theory. Fluid velocity potential is acquired using the Laplace equation, and fluid boundary conditions and wet dynamic ...

The role that the pattern of vessel wall growth plays in determining pressure-lumen area (P-A) and pressure-compliance curves was examined. A P-A vessel model was developed that encompasses the complete range of pressure, including negative values, and accounts for size given the fixed length, nonlinear elastic wall properties, constant wall area, and collapse. Data were obtained from excised c...

Blood vessel constriction is simulated with particle-based method using a molecular dynamics authoring software known as Molecular Workbench (WM). Blood flow and vessel wall, the only components considered in constructing a blood vessel, are all represented in particle form with interaction potentials: Lennard-Jones potential, push-pull spring potential, and bending spring potential. Influence ...

Secondary lymphatic valves are essential for minimizing backflow of lymph and are presumed to gate passively according to the instantaneous trans-valve pressure gradient. We hypothesized that valve gating is also modulated by vessel distention, which could alter leaflet stiffness and coaptation. To test this hypothesis, we devised protocols to measure the small pressure gradients required to op...

Many real-world search and optimization problems involve inequality and/or equality constraints and are thus posed as constrained optimization problems. In trying to solve constrained optimization problems using classical optimization methods, this paper presents a Multi-Objective Bees Algorithm (MOBA) for solving the multi-objective optimal of mechanical engineering problems design. In the pre...