background: immunophenotypic characterization of the leukemic cells has been widely used as a tool for diagnosis, classification, stratification and prognosis of leukaemia. objective: to investigate the immunophenotypic subtype profiles of iranian patients with acute lymphoblastic leukemia (all) and its association to disease outcome. methods: in this study, a total of 60 iranian patients with ...

Among the six classes of pro-2-groups of finite and fixed co-classes and trivial Schur Multiplicator which studied by Abdolzadeh and Eick in 2009, there are two classes $$S_5=langle a,bmid [b,a^2]=1, a^2=[b,a]^2, (b^2)^{[b,a]}b^2=1rangle$$ and $$S_6=langle a,t,bmid a^2=b^2,[b,a]^2=1, t^a=t^{-1}[b,a], b^t=abarangle$$that have been conjectured to have deficiency zero presentations. In this paper ...

among the six classes of pro-2-groups of finite and fixed co-classes and trivial schur multiplicator which studied by abdolzadeh and eick in 2009, there are two classes $$s_5=langle a,bmid [b,a^2]=1, a^2=[b,a]^2, (b^2)^{[b,a]}b^2=1rangle$$ and $$s_6=langle a,t,bmid a^2=b^2,[b,a]^2=1, t^a=t^{-1}[b,a], b^t=abarangle$$that have been conjectured to have deficiency zero presentations. in this paper ...

conclusions the results of the current study suggested that spinal anesthesia plus intravenous patient-controlled analgesia have the most favorable cardiac effects regarding postoperative levels of pro-bnp. results there was no difference between three groups for basic characteristics and variables and baseline pro-bnp levels; however, postoperative pro-bnp levels in groups a, b, and c were res...

Activation-induced cytidine deaminase (AID) is essential for somatic hypermutation and class switch recombination in mature B-cells, while AID was also shown to play a role in developing pre-BCR/BCR-positive B-cells of the bone marrow. To further elucidate a potential function of Aid in the bone marrow prior to V(D)J-recombination, we utilized an in vivo model which exerts a B-cell developmenta...

A number of presumptive target genes for the Ets-family transcription factor PU.1 have been identified in the B cell lineage. However, the precise function of PU.1 in B cells has not been studied because targeted null mutation of the PU.1 gene results in a block to lymphomyeloid development at an early developmental stage. In this study, we take advantage of recently developed PU.1(-/-)Spi-B(-/...

Mice homozygous for the scid (severe combined immunodeficiency) mutation are generally unable to produce B lymphocytes, a condition attributed to defective rearrangement of immunoglobulin genes in precursor B cells. Some early B-lineage cells are present in the bone marrow (BM), however. In scid mice, we defined three subsets of early progenitor B cells lacking mu heavy chains (pro-B cells) bas...