Introduction: Recently, an approach exploiting the proton therapy biological enhancement by using Boron atoms injected inside a tumor, has been proposed. Three alpha particles with an average energy around 4MeV are emitted from the point of reaction between a proton and boron. In addition, the 719 keV prompt gamma emitted by the proton Boron fusion reactions can be used for on-...

The aim of this study is to compare between proton boron fusion therapy (PBFT) and boron neutron capture therapy (BNCT) and to analyze dose escalation using a Monte Carlo simulation. We simulated a proton beam passing through the water with a boron uptake region (BUR) in MCNPX. To estimate the interaction between neutrons/protons and borons by the alpha particle, the simulation yielded with a v...

The purpose of this study is to evaluate the prompt gamma ray imaging technique according to the clinical boron concentration range during proton boron fusion therapy (PBFT). To acquire a prompt gamma ray image from 32 projections, we simulated four head single photon emission computed tomography and a proton beam nozzle using a Monte Carlo simulation. We used modified ordered subset expectatio...

In this study, we propose a tumor monitoring technique using prompt gamma rays emitted from the reaction between an antiproton and a boron particle, and verify the improvement of the therapeutic effectiveness of the antiproton boron fusion therapy compared with proton and antiproton beam without boron. The tumor monitoring system during the antiproton therapy was simulated using the Monte Carlo...

Abstract The proton-boron aneutronic fusion reaction has numerous potential applications varying from controlled nuclear reactor to broad-energy spectrum α-particle source, as well uses in medicine, where it can serve a source for radioisotope production, or directly proton boron capture therapy. However, and its by-products should be investigated extensively provide stable secondary ion source...

the ionization effects of charged particles produced in neutron interactions for boron neutroncapture therapy are considered here using srim monte carlo code. the estimated values of these effects ina plexiglas acrylic phantom are shown to agree well with the available experimental values in high boronconcentration areas. as expected, the ionization effects from lithium and alpha particles are ...

Abstract Recent experiments with high-intensity lasers have shown record production of α -particles by irradiating boron-hydrogen targets. This opened the way to completely new studies on proton-boron fusion multiple goals: i) related nuclear fusion. The reaction produces 3 and releases a large energy. It is considered an interesting alternative deuterium-tritium because it no neutrons, therefo...