OBJECTIVE Perovskia abrotanoides Karel, belongs to the family Lamiaceae and grows wild alongside the mountainous roads inarid and cold climate of Northern Iran. The anti-tumor activity of P. abrotanoides root extract has been shown previously. This study was designed to examine in vitro anti-proliferative and pro-apoptotic effects of flower extract of P. abrotanoides on MCF-7 and Hela cell line...

Phytochemical study on the ethanol extract of the aerial parts of Carpesium abrotanoides led to the isolation of two new sesquiterpene lactones, carabrolactone A (1) and carabrolactone B (2). Their structures were elucidated on the basis of extensive spectroscopic analysis.

BACKGROUND Perovskia abrotanoides Karel. is a medicinal plant used in Iranian folk medicine as a pain killer. Forty-one components have been identified in P. abrotanoides samples collected from Baluchistan Province, and 29 components have been recognized in samples collected from Khorasan Province. The leaves of P. abrotanoides have glandular trichomes (capitates and peltate) on both sides of t...

OBJECTIVE Sleeplessness is the most common sleep disorder. In this study the hypnotic effect of the hydro-alcoholic extract (HAE) of Perovskia abrotanoides Karel. and its water fraction (WF), ethyl acetate fraction (EAF) and n-butanol fraction (NBF) were studied in mice. MATERIALS AND METHODS The test compounds were administered intraperitoneally to mice 30 min before the administration of so...

In Iranian folk medicine, Perovskia abrotanoides is used for treatment of leishmaniasis. These patients may develop secondary infections with opportunistic microorganisms. Therefore, the antimicrobial activity of essential oil from aerial part of P. abrotanoides and its main components was evaluated against different microorganisms. Disc diffusion and broth micro dilution assays were used for i...

objective: perovskia abrotanoides karel, belongs to the family lamiaceae and grows wild alongside the mountainous roads inarid and cold climate of northern iran. the anti-tumor activity of p. abrotanoides root extract has been shown previously. this study was designed to examine in vitro anti-proliferative and pro-apoptotic effects of flower extract of p. abrotanoides on mcf-7 and hela cell lin...