background: the interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries. objective: to understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from c...

Arterial drug concentration distribution determines local toxicity. The safety issues dealt with Drug-Eluting Stents (DESs) reveal the needs for investigation about the effective factors contributing to fluctuations in arterial drug uptake. The current study focused on the importance of hypertension as an important and controversial risk factor among researchers on the efficacy of Heparin-Eluti...

In this article, dynamics of the cerebrospinal fluid (CSF) was studied, using computational fluid dynamics. Using MRI images of two special cases, a 2-dimensional model of the ventricular system was made. CSF velocity and pressure distribution in ventricular system have high importance since the flow pattern of this liquid has an important effect on intracranial pressure, i.e., ICP, which has a...

in this article, dynamics of the cerebrospinal fluid (csf) was studied, using computational fluid dynamics. using mri images of two special cases, a 2-dimensional model of the ventricular system was made. csf velocity and pressure distribution in ventricular system have high importance since the flow pattern of this liquid has an important effect on intracranial pressure, i.e., icp, which has a...

Enhancement of heat and mass transfer and decrease of energy dissipation are great necessities of the evolution of fluid flow devices. Utilizing oscillatory or pulsatile fluid flow for periodic disturbing of velocity and thermal boundary layers is one of the methods with exciting results. Passive methods of generating oscillatory flow are preferred to active methods because of simplicity, no ne...

The aqueous outflow system is unique because nowhere else can the pattern of flow of an extravascular fluid be directly observed as it returns to the vascular system. Such observations reveal that aqueous flow both from Schlemm's canal into the aqueous veins and from the aqueous veins into the episcleral veins is pulsatile. Pulsatile aqueous flow mechanisms are observable in vivo not only in no...

AIMS To investigate the effect of central corneal thickness and corneal curvature on intraocular pressure measurements using the pulsatile ocular blood flow tonograph and the Goldmann applanation tonometer, and to assess the agreement between the pulsatile ocular blood flow tonograph and the Goldmann applanation tonometer in intraocular pressure measurement. METHODS 479 subjects underwent int...

he advent of cardiopulmonary bypass (CPB) has enabled cardiovascular surgeons to perform complex, life-saving procedures with relative ease while protecting end-organ function. Altering the normal pulsatile blood flow to non-pulsatile continuous flow has raised concerns over potential detrimental hemodynamic and physiologic consequences. Concerns over long-term non-pulsatile flow drove the desi...

BACKGROUND Decellularized animal organs have been used as scaffolds for tissue engineering. To make a properly functioning scaffolds, the extracellular matrix (ECM) components must be preserved after decellularization. Because pulsatile flow is known to be beneficial for tissue perfusion, pulsatile perfusion of a detergent might decrease the exposure time of the tissues to the detergent used fo...

Sickle cell disease (SCD) is characterized by microvascular occlusion mediated by adhesive interactions of sickle erythrocytes (SSRBCs) to the endothelium. Most in vitro flow adhesion assays measure SSRBC adhesion during continuous flow, although in vivo SSRBC adhesive interactions occur during pulsatile flow. Using a well-plate microfluidic flow adhesion system, we demonstrate that isolated SS...