Fusion genes: Ewing sarcoma: t(11;22)(q24;q12) EWS-FLI1 t(21;22)(q22;q12) EWS-ERG t(7;22)(p22;q12) EWS-ETV1 others FUS-ERG, EWS-FEV, Desmoplastic SRCT: t(11;22)(p13;q12) EWS-WT1 Extraskel myxoid chondrosarc: t(19;22)(q22;q12) EWS-TEC(CHN) Malignant mesenchymoma: t(11;22)(q24;q12) EWS-FLI1 Alveolar rhabdomyosarcoma: t(2;13)(q35;q14) PAX3-FKHR t(1;13)(p36;q14) PAX7-FKHR Myxoid round cell liposarc...

t(11;22)(q24;q12) FLI1-EWSR1 85 ETS t(21;22)(q22;q12) ERG-EWSR1 5–15 t(7;22)(p22;q12) ETV1-EWSR1 <1 t(17;22)(q12;q12) E1AF-EWSR1 <1 t(2;22)(q33;q12) FEV-EWSR1 <1 patients and characterized by adverse outcome. Recently our understanding of molecular pathogenesis of Ewing sarcoma has greatly progressed, and there have been some promising therapeutic advances. The cytogenetic hallmark of Ewing sar...

We present a case of acute myeloid leukemia (AML) with a balanced translocation between chromosomes 2q12 and 6q12, t(2;6)(q12;q12). This abnormality was defined by conventional cytogenetics and multicolor banding techniques using specific probes for chromosome 2. Blasts accounted for 2% of white blood cells in peripheral blood and approximately 30% of all nucleated cells in marrow aspirates. Th...