OBJECTIVE The purpose of this article is to examine the case for and challenges to implementing random breath testing (RBT) in Canada, with a particular focus on the persistence of impaired driving under the current method of law enforcement. It seeks to place RBT within Canada's existing legal and social framework. METHODS This article reviews Canada's impaired driving record, charge and con...

Didanosine (ddI) is currently used in the management of patients infected by the human immunodeficiency virus. Rifabutin (RBT) is being extensively used for prophylaxis against Mycobacterium avium complex (MAC) infections. Due to its acid-labile characteristics, ddI must be administered with a buffer. Recent reports have indicated that absorption of ketoconazole, ciprofloxacin, and dapsone, etc...

Background Random breath testing (RBT) aimed at general deterrence of drink-driving has been shown to be more effective than targeted alcohol screening from patrol cars aimed at apprehending drink-drivers. The European PEPPER study’s meta-analysis of 40 evaluations found that the largest crash reductions were achieved by Australian methods of RBT (involving use of highvisibility bus-based testi...

In Australia, legislation prohibiting driving while under the influence of alcohol is enforced through random breath testing (RBT). RBT empowers police to test drivers at any time, irrespective of whether they exhibit behaviour that indicates the prior consumption of alcohol. Research into the effectiveness of RBT has demonstrated a largely positive impact on the harms associated with drink dri...

We used radiotelemetry to assess spatial and temporal spawning distributions of native westslope cutthroat trout (Oncorhynchus clarkii lewisi; WCT), introduced rainbow trout (Oncorhynchus mykiss; RBT), and their hybrids in the upper Flathead River system, Montana (USA) and British Columbia (Canada), from 2000 to 2007. Radio-tagged trout (N = 125) moved upriver towards spawning sites as flows in...

OBJECTIVE To test agreement of two methods to measure intraocular pressure (IOP): rebound tonometry (RBT) and gold standard Goldmann applanation tonometry (GAT) in children with glaucoma. DESIGN Observational prospective cohort study. SETTING Tertiary paediatric glaucoma clinic at a single centre. PARTICIPANTS 102 individuals attending a paediatric glaucoma clinic, mean (SD) age 11.85 (3....

PURPOSE High intraocular pressure (IOP) is an important risk factor for a variety of pediatric ophthalmic conditions. The purpose of this study is to evaluate the feasibility, length of examination, and corneal epithelial damage induced by rebound tonometry (RBT) versus Goldmann applanation tonometry (GAT) in school children. METHODS Healthy children (n=57) participated in a randomized, trans...

OBJECTIVE This study aims to apply time series analysis techniques to examine the effects of random breath testing (RBT) on three age-specific traffic fatalities in four Australian states while considering the effects of lowering the minimum legal drinking age (MLDA). METHODS Long-term time series of age-specific traffic crash deaths in four Australian states were used to analyse the impact o...

RBT-K5 cell line was established from a male Wistar rat bladder tumor induced with N-butyl-N-(4-hydroxybutyl) nitrosamine. RBT-K5 (ADM res.) cell line, adriamycin (ADM) resistant, was also established from RBT-K5 cells by stepwise escalation of ADM concentrations in vitro. In this study, we have examined the effect of verapamil (VR) on intracellular ADM concentration in these cell lines. The vi...

AIMS Fecal incontinence (FI) is embarrassing, resulting in poor quality of life. Rectal sensation may be more important than sphincter strength to relieve symptoms. A single-blind, randomized controlled trial among adults with FI compared the effectiveness of rectal balloon training (RBT) and pelvic floor muscle training (PFMT) versus PFMT alone. METHODS We randomized 80 patients, recruited f...