Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder. Various constituents including flavonoids with biological activities including free radical scavenging, anti-lipoperoxidation and anti-inflammatory have been isolated from hawthorn. Due to adverse effect of PCOS on ovarian vascular remodeling as well as PCOS-induced oxidative stress, we aimed to study the hawthorn’s berri...

Background: Nanosilver (NS) contains silver nanoparticles to control infections delivered from bacteria. The NS compounds as well as being toxic to prokaryotes are highly toxic to mammalian cells. The present study was evaluated the effect of colloidal NS on leydig cells glucose transporter type I (GLUT I) expression, serum level of testosterone, germinal cells RNA damage and spermiogenesis pro...

RNA in a cell is subject to many of the same insults as DNA. RNA damage can induce apoptosis and may be exploited for anti-cancer chemotherapy. It is a surprise, however, to learn that cells may repair RNA damage, suggesting a far greater significance of RNA in genotoxic stress.

Background: Deltamethrin (DTM) is a pyrethroid derivative, which is the most potent products of Type 2 insecticides and acts by delaying the closure of sodium channels. Estrogen as a vascular growth factor on ovarian tissue plays an essential impact further to its involvement in follicular growth. On the other hand, the role of angiogenesis on ovarian tissue in inhibiting the apoptotic provoker...

Background: Varicocele (VCL) impacts the testicular tissue partly by down-regulating the antioxidant status accomplished with reducing the intra-testicular endocrine potential. It has been reported that the HSP70 families play a critical role in spermiogenesis. Therefore, current study was aimed to evaluate the protective effect of exogenous testosterone and vitamin E administration on VCL-indu...

Background: Nano-particle Titanium Dioxide (TiO2) is a noncombustible, odorless powder that is widely used in different fields of industries. Previous reports showed that chronic exposure to TiO2 adversely impacts the testicular tissue and down-regulates the antioxidant capacity and down-regulates the endocrine status of the testicles. Present study was designed in order to identify the role of...