complex inherited diseases affected by an interaction between collective effects of the genotype at one or multiple loci either to increase or to lower susceptibility to disease, combined with a variety of environmental exposures that may trigger, accelerate, exacerbate, or protect against the disease process. the new aspects of genetic techniques have been opened for diagnosis and analysis of ...

background: breast cancer is the most common cancer and the leading cause of cancer death among the women worldwide. the risk of local and distant recurrence is the highest during the first two years following the initial treatment. very late relapse (after 12 years) is uncommon in breast cancer survivors. methods: herein, we report the characteristics and outcomes of 6 such cases of breast can...

background and purpose: the relationship between uric acid and stroke recurrence is ambiguous. some studies have explored this relationship in acute ischemic stroke but had different results. we evaluated the association of admission uric acid level with risk of stroke recurrence in patients with ischemic stroke. methods: we studied ischemic stroke patients presenting to our hospital with magne...

background and aim: carcinoma of the uterine cervix is a significant cause of mortality because of malignancy in women. radiotherapy is a major treatment modality for invasive cervical cancer with good treatment outcome in early-stage patients. however, substantial treatment failures still occur in the advanced-stage patients. in this case report a long term follow up of a 58 years old woman wi...

objective febrile seizure is the most common problem in pediatric neurology that occurs in 3- 4 % of children. the purpose of this study was to determine febrile seizure recurrence frequency and to evaluate its risk factors. materials & methods in a descriptive prospective study, 139 children (6 months to 6 years) with first febrile seizure were admitted to yazd shaheed sadoughi hospital betwee...

conclusions: relationships between the spiritual intelligence and resiliency parameters with withdrawal time show that these parameters can have a role in relapse protection among addicted people. results: there were significant positive correlations between resiliency and scores of spiritual intelligence as well as with subscales of spiritual intelligence. in addition, there were significant p...

results there was no statistical difference between the 2 groups with respect to the recurrence rate (p > 0.05). although the recurrence interval was longer for the metformin group, this increase was not statistical significant (p > 0.05). furthermore, tumor recurrence had no correlation with sex or the grade of the tumors. conclusions according to our findings, it seems that metformin has no c...

purpose: to report the clinical, radiological, pathological and therapeutic features of a case of recurrent cavernous hemangioma. case report: a 32 year old lady with progressive decrease of vision in her right eye associated with blepharoptosis was diagnosed to have orbital cavernous hemangioma which was excised. 10 years later she presented with recurrent proptosis and progressive eye deviati...

background postoperative relapse is a common feature of crohn's disease (cd) in western countries but its frequency and risk factors have not been studied in the middle east where there is a rapid upsurge in the incidence of cd. this study aims to research the frequency and risk factors of its recurrence after surgery among 566 iranian patients with cd in tehran, iran. methods all 566 patients ...

background upper gastrointestinal bleeding (ugib) is a major healthcare problem and is the most frequent gastrointestinal reason for admission to hospital. we aimed to investigate the prognosis of patients with ugib referred to a referral hospital in northern iran in 2013. methods all patients with ugib who admitted to sayyad shirazi hospital, in gorgan, northern iran, in 2013 were enrolled. th...