background: acute promyelocytic leukemia (apl) is a subclass of acute myeloid leukemia. the chromosomal aberration in 95% of apl cases is t(15; 17) (q22; q21), which prevents cell differentiation. characterization of the underlying molecular lesion is valuable in determining optimal treatment strategy. the goal of this study was to develop a new and powerful flow- fish technique to detect the l...

Arterial stenosis, for example Atherosclerosis, is one of the most serious forms of arterial disease in the formation of which hemodynamic factors play a significant role. In the present study, a 3-D rigid carotid artery with axisymmetric stenosis with 75% reduction in cross-sectional area is considered. Laminar blood flow is assumed to have both Newtonian and non-Newtonian behavior (generalize...

A severe case of stenosis in coronary arteries results in turbulence in the blood flow which may lead to the formation or progression of atherosclerosis. This study investigated the turbulent blood flow in a coronary artery with rigid walls, as well as 80% single and double stenoses on blood flow. A finite element-based software package, ADINA 8.8, was employed to model the blood flow. The hemo...