نتایج جستجو برای: Rosmarinic acid

تعداد نتایج: 747477  

Journal: :Food technology and biotechnology 2016
Zoran Zorić Joško Markić Sandra Pedisić Viljemka Bučević-Popović Ivana Generalić-Mekinić Katarina Grebenar Tea Kulišić-Bilušić

The present study compares the gastrointestinal stability of rosmarinic acid in aqueous extracts of thyme, winter savory and lemon balm with the stability of pure rosmarinic acid. The stability of rosmarinic acid was detected after two-phase in vitro digestion process (gastric and duodenal) with human gastrointestinal enzymes. The concentration of rosmarinic acid in undigested and digested samp...

Journal: :Zeitschrift fur Naturforschung. C, Journal of biosciences 2004
Natasa Bauer Dunja Leljak-Levanic Sibila Jelaska

Agrobacteria mediated Coleus blumei tumour tissues were cultured in vitro on MS medium. Sixteen diversified transformed callus cultures were maintained for several years in the absence of plant growth regulators and antibiotics without affecting the growth rate. Rosmarinic acid was detected spectrophotometrically in all tissue lines but in different quantities. The highest rosmarinic acid accum...

2010
Ronald S. Fletcher Tannis Slimmon Laima S. Kott

Four spearmint, and two peppermint clonal lines, selected for enhanced rosmarinic acid content (50-120 mg g -1 rosmarinic acid DW), where up to 80% of the antioxidant activity was correlated to rosmarinic acid content, were examined to determine the effects of environmental and physiological conditions on the accumulation of rosmarinic acid in leaf tissues. Exposure to a short photoperiod of 12...

Journal: :Biochemical pharmacology 2007
Jongsung Lee Yeong Shik Kim Deokhoon Park

Melanogenesis is a physiological process that results in the synthesis of melanin pigments, which play a crucial protective role against skin photocarcinogenesis. In order to determine the effects of rosmarinic acid on melanogenesis and elucidate the molecular events of melanogenesis induced by rosmarinic acid, several experiments were performed in B16 melanoma cells. In this study, we showed t...

Journal: :iranian journal of basic medical sciences 0
majid tavafi department of anatomy, faculty of medicine, lorestan university of medical sciences and razi herbal researches center, lorestan university of medical sciences, khoram abad, iran hasan ahmadvand department of biochemistry, faculty of medicine, lorestan university of medical sciences, khoram abad, iran alireza khalatbari department of anatomy, faculty of medicine, lorestan university of medical sciences, khoram abad, iran ahmad tamjidipoor department of anatomy, faculty of medicine, lorestan university of medical sciences, khoram abad, iran

objective(s) oxidative stress plays an important role in diabetic nephropathy pathogenesis. rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. material and methods forty male rats were uninephrectomized from the left flank.the rats were divided in four groups randomly; group one as control, group two diabetic untreatment, g...

2015
Moeko Noguchi-Shinohara Kenjiro Ono Tsuyoshi Hamaguchi Kazuo Iwasa Toshitada Nagai Shoko Kobayashi Hiroyuki Nakamura Masahito Yamada

The aim of this study was to evaluate the safety, tolerability and pharmacokinetics of single dose of Melissa officinalis extract which contained rosmarinic acid, including food-effects in healthy individuals. A total of eleven healthy individuals were randomly assigned to treatment arms in the two studies [Study 1 (fasted state) and Study 2 (fed state)]. Rosmarinic acid in serum was measured b...

Journal: :Food technology and biotechnology 2015
Nataša Bauer Rosemary Vuković Saša Likić Sibila Jelaska

Rosmarinic acid is one of the main active components of Coleus blumei and is known to have numerous health benefits. The pharmacological significance of rosmarinic acid and its production through in vitro culture has been the subject of numerous studies. Here, the ability of different tissues to accumulate rosmarinic acid and sustainability in production over long cultivation have been tested. ...

Journal: :Planta medica 2017
Christian G Kirchler Cornelia K Pezzei Krzysztof B Beć Raphael Henn Mika Ishigaki Yukihiro Ozaki Christian W Huck

The present study evaluates the analytical performance of near infrared as well as attenuated total reflection infrared spectroscopy for the determination of the rosmarinic acid content in Rosmarini folium. Therefore, the recorded near infrared and attenuated total reflection infrared spectra of 42 milled Rosmarini folium samples were correlated with reference data (range: 1.138-2.199 rosmarini...

2012
Maike Petersen A. W. Alfermann

Rosmarinic acid biosynthesis can be stimulated in cell cultures of Coleus blumei by culturing the cells in medium with 4% sucrose. In enzyme extracts of these cells two new enzymes of rosmarinic acid biosynthesis were discovered. Hydroxyphenylpyruvate reductase reduces 4-hydroxyphenylpyruvate and 3,4-dihydroxyphenylpyruvate to 4-hydroxyphenyllactate and 3,4-dihydroxyphenyllactate, respectively,...

Journal: :international journal of advanced biological and biomedical research 2014
mh. kiani a. mokhtari h. zeinali a. abbasnejad l. afghani khoraskani

melissa officinalis l. is a well-known medicinal plant from the family of lamiaceae. the plant is high in flavonoid. flavonoids of lemon balm such as rosmarinic acid and anthocyanin have an antiviral and antioxidant effect. micronutrients are the element that is necessary for the plant in low concentration. in this experiment the effect of micronutrient (fe and zn) was examined on the anthocyan...

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