Background & Aims: Diarrheal diseases are one of the major causes of morbidity and mortality in infants and toddlers in developing countries and Rotavirus is the single most important cause of severe infantile gastroenteritis worldwide. This study was conducted to estimate the frequency and clinical manifestations of rotavirus infection in children below 3 years old with acute gastroenteritis r...

Background and Aims: Rotaviruses are one of the main causative agents of acute viral gastroenteritis in both young human and animals. Several methods have been used for diagnosis of rotavirus infection. Most of these methods are not easily available in Iran. Methods: In our study attempt was made to develop a method which could replace the commercially imported Kit. Rota virus was purified and...

Background and Aims: In humans the group A rotaviruses are associated with endemic diarrhea in children under the age of 5, leading to approximately 800,000 deaths every year. Introduction of rotavirus vaccines into childhood immunization programs can contribute to substantial reduction in mortality from rotavirus gastroenteritis in developing countries and virtually eliminating hospitalization...

Abstract Acute diarrhea with severe dehydration has been a major worldwide cause of death in children younger than 5 years of age. Etiological studies of gastroenteritis have shown that rotavirus causes 40–50% of acute diarrhea among infants and children in both developing and developed nations. Numerous epidemiologic studies in the US and the World Health Organization have docu...

Background and Aims: One of the major causes of acute diarrhea in children during the cold season in Iran is infection by rotavirus. Children infected with rotavirus often require hospitalization. Several studies on human and animals have shown that enterotoxigenic Escherichia.coli and rotavirus are the most common coinfection causing diarrhea. There are other reports indicating occurrence of r...

abstract acute diarrhea with severe dehydration has been a major worldwide cause of death in children younger than 5 years of age. etiological studies of gastroenteritis have shown that rotavirus causes 40–50% of acute diarrhea among infants and children in both developing and developed nations. numerous epidemiologic studies in the us and the world health organization have documented the clini...

background: rotaviruses cause diarrhea in infants and young children worldwide. rotavirus outer capsid protein, vp7 is major neutralizing antigen that is important component of subunit vaccine to prevent rotavirus infection. many efforts have been done to produce recombinant vp7 that maintain native characteristics. we used baculovirus expression system to produce rotavirus vp7 protein and to s...

Rotaviruses are the most common cause of severe diarrhea in children under 5 years of age worldwide with a higher prevalence in developing countries. In accordance with the World Health Organization (WHO) recommendations for the global use of rotavirus vaccines, it is important to review trends of rotavirus epidemiology, distribution and diversity of rotavirus strains in the pre-vaccine period....

background and aims: one of the major causes of acute diarrhea in children during the cold season in iran is infection by rotavirus. children infected with rotavirus often require hospitalization. several studies on human and animals have shown that enterotoxigenic escherichia.coli and rotavirus are the most common coinfection causing diarrhea. there are other reports indicating occurrence of r...