Spinophilin controls intensity/duration of G protein-coupled receptor signaling and thereby influences synaptic activity. We hypothesize that spinophilin affects blood pressure through central mechanisms. We measured blood pressure and heart rate in SPL-deficient (SPL(-/-)), heterozygous SPL-deficient (SPL(+/-)), and wild-type (SPL(+/+)) mice by telemetry combined with fast Fourier transformati...

Gender equality is integral to a universities’ strategy and agenda. However, there gap when looking through the lens of shared parental leave (SPL) or breastfeeding. This research investigates causal relationship between SPL, breastfeeding, workplace support. A survey targeting women working in UK Higher Education Institutions was conducted February July 2021, 49 completed responses were record...

A Software Product Line (SPL) is a set of related programs. A SPL of a SPL (SPL), or a product line of a product line, is a fundamental scaling of product line concepts. A member of a SPL is not a program, but a SPL. The idea recurses: a SPL is a SPL of a SPL, and so on. The depth of recursion is the rank of the product line. We present an algebra to understand and build feature-based product l...

The battery of electric vehicles (EV) can be charged from the power grid or discharged back to it. Parking lots can aggregate hundreds of EVs which makes them a significant and flexible load/generation component in the grid. In a smart grid environment, the smart parking lot (SPL) can benefit from the situation of the simultaneous connection to the EVs and power grid. This paper proposes a new ...

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that activates a family of G protein coupled-receptors (GPCRs) implicated in mammalian development, angiogenesis, immunity and tissue regeneration. S1P functions as a trophic factor for many cell types, including embryonic stem cells (ESCs). Sphingosine phosphate lyase (SPL) is an intracellular enzyme that catalyzes the irreversible degr...

Objetivo: Avaliar o a influência da remoção de resíduos dois cimentos à base resina epóxi (SPL, Sealer Plus ou S26, 26), com etanol 95% (ETA) xilol (XIL), na interface adesão entre sistema adesivo universal (SBU, Scotchbond Universal), utilizado estratégia condiciona-e-lava, e substrato dentinário coroa dental, por meio avaliação resistência união (RU), avaliada pelo teste microcisalhamento, an...