Background: Salivary gland tumors (SGT) are rare lesions with uncertain histopathology. One of the major signaling pathways that participate in the development of several tumors is protein kinase A. In this pathway, glycogen synthase kinase β (GSK3β) and cAMP responsive element binding protein (CREB3) are two genes which are supposed to be down regulated in most human tumors. The expression lev...

Salivary duct carcinoma is a very rare, highly-malignant epithelial tumour. We present a case of a 75-year-old man with a rapidly- growing salivary duct carcinoma in the parotid gland, of one month's evolution. Histopathologically, salivary duct carcinoma is characterised by its resemblance to ductal carcinoma of the breast. It usually develops aggressively with possibilities of early distant m...

A 40-year old male presented with rapidly growing swelling in the right parotid region. Based on the fine needle aspiration cytology report of adenocarcinoma not otherwise specified, superficial parotidectomy was performed, which showed the features of salivary duct carcinoma by histopathological examination. The smears were reviewed to identify the potential pitfalls in the cytological diagnos...

background: salivary gland tumors (sgt) are rare lesions with uncertain histopathology. one of the major signaling pathways that participate in the development of several tumors is protein kinase a. in this pathway, glycogen synthase kinase β (gsk3β) and camp responsive element binding protein (creb3) are two genes which are supposed to be down regulated in most human tumors. the expression lev...

Introduction Carcinomas of the salivary glands represent a rare tumor group. The following is case hepatic metastatic carcinoma duct. patient presented due to indolent swelling left parotid gland with extension ipsilateral cervical lymph nodes and facial nerve paresis.

Dear Editor, Salivary duct carcinomas (SDC) are primarily high-grade, aggressive malignancies that affect men in the fi fth and sixth decades of life. These tumours are primarily found in the major salivary glands, especially parotid and are rarely from minor salivary glands. If it involves the minor salivary gland, the most common reported sites include the paranasal sinuses and intraoral cavi...

BACKGROUND Salivary duct carcinoma with rhabdoid features is extremely rare. METHODS We report 2 cases of salivary duct carcinoma with rhabdoid features treated at our institution. RESULTS Case 1 was a 44-year-old Japanese man who had swelling in the left parotid region. This tumor consisted of residual pleomorphic adenoma and widely invasive carcinoma, which showed a diffuse growth pattern...

BACKGROUND Salivary duct carcinoma, an aggressive subtype of salivary gland cancer, is mostly androgen receptor-positive. Only limited data are available on androgen deprivation therapy (ADT). METHODS Patients with advanced androgen receptor-positive salivary duct carcinoma treated with first-line ADT were retrospectively evaluated for clinical benefit (ie, partial response [PR] and stable di...

Systemic therapy for salivary gland carcinoma (SGC) is indicated recurrent and/or metastatic (RM) disease. The background, goals of therapy, organ function, symptomatic or a symptomatic, and histopathology should be considered in each case. Adenoid cystic with only lung metastasis often progresses slowly many cases are followed up without whereas duct carcinoma, adenocarcinoma NOS, adenoid mult...