نتایج جستجو برای: Sandwich format

تعداد نتایج: 159283  

2016

A leading application of biomolecular interaction analysis technology is the characterization of antibodyantigen interactions. By measuring the association and dissociation rates of the interaction, antibodies with desired binding characteristics can be identified. A rapid association rate and a slow dissociation rate may be indicative of therapeutic efficacy. Affinity maturation programs exist...

Journal: :Journal of magnetism and magnetic materials 2011
Ariel Hecht Paivo Kinnunen Brandon McNaughton Raoul Kopelman

This paper presents a novel application of magnetic particles for biosensing, called label-acquired magnetorotation (LAM). This method is based on a combination of the traditional sandwich assay format with the asynchronous magnetic bead rotation (AMBR) method. In label-acquired magnetorotation, an analyte facilitates the binding of a magnetic label bead to a nonmagnetic solid phase sphere, for...

Journal: :Bioinformatics 2001
Frédéric Tores Emmanuel Barillot

MOTIVATION Giving a meaningful representation of a pedigree is not obvious when it includes consanguinity loops, individuals with multiple mates or several related families. RESULTS We show that finding a perfectly meaningful representation of a pedigree is equivalent to the interval graph sandwich problem and we propose an algorithm for drawing pedigrees.

Journal: :Public health nutrition 2013
Áine P Hearty Michael J Gibney

OBJECTIVE Pattern analysis of adolescent diets may provide an important basis for nutritional health promotion. The aims of the present study were to examine and compare dietary patterns in adolescents using cluster analysis and principal component analysis (PCA) and to examine the impact of the format of the dietary variables on the solutions. DESIGN Analysis was based on the Irish National ...

2017
C.F. Markwalter I.K. Jang R.A. Burton G.J. Domingo D.W. Wright

Predicting antibody pair performance in a sandwich format streamlines development of antibody-based diagnostics and laboratory research tools, such as enzyme-linked immunosorbent assays (ELISAs) and lateral flow immunoassays (LFAs). We have evaluated panels of monoclonal antibodies against the malarial parasite biomarker Plasmodium falciparum histidine rich protein 2 (HRP2), including 9 new mon...

2015
Kyeong-Ah Lee Ji-Young Ahn Sang-Hee Lee Simranjeet Singh Sekhon Dae-Ghon Kim Jiho Min Yang-Hoon Kim

We validated a single-stranded, DNA aptamer-based, diagnostic method capable of detecting Lipocalin-2 (LCN2), a biomarker from clinically relevant hepatocellular carcinoma (HCC) patient serum, in the sandwich assay format. Nine aptamers (LCN2_apta1 to LCN2_apta9) for LCN2 were screened with SELEX processes, and a sandwich pair (LCN2_apta2 and LCN2_apta4) was finally chosen using surface plasmon...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2016
Jonathan P Jackson Linhou Li Erica D Chamberlain Hongbing Wang Stephen S Ferguson

Over the last decade HepaRG cells have emerged as a promising alternative to primary human hepatocytes (PHH) and have been featured in over 300 research publications. Most of these reports employed freshly differentiated HepaRG cells that require time-consuming culture (∼28 days) for full differentiation. Recently, a cryopreserved, predifferentiated format of HepaRG cells (termed here "cryo-Hep...

2017
R. Alan Wilson

Article history: Received 2 October 2017 Accepted 2 October 2017 Available online 3 October 2017 tests used specific monoclonal antibodies in a sandwich ELISA to detect the antigens in sera and urine but the technique has been progressively improved and converted to dipstick format for non-invasive, point-ofcare testing on urine samples (the POC-CCA cassette). Although this appears to be more s...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید