Dried stem bark extracts of Saraca asoca Roxb. Prepared by different extraction methods (Soxhlet, Ultrasonication assisted & Microwave assisted extraction) with ethanol 90%, ethanol 60% and acetone. The acetone extract prepared by Ultrasonication assisted extraction, showed significant antidiarrhoeal property in castor-oil induced diarrhoea in albino rats at a dose of 200 mg/kg, b.w. as compare...

S. Gomathi and K.M. Subbu Rathinam* ABSTRACT To identify the insecticidal components of Saraca asoca bark were evaluated by standard protocol using the equipment Perkin-Elmer Gas Chromatography–Mass Spectrometry. The mass spectrum of the compounds found in the extract was matched with the National Institute of Standards and Technology (NIST) library. The GC-MS analysis revealed the presence of ...

The study was conducted to screen for the phytochemicals constituents of bark of Saraca asoca (Roxb.), one of the folk medicinal plants found in West Bengal, Bangladesh and Sri Lanka. The acute and subacute toxicity of methanolic extract of S. asoca bark on mice was studied. Phytochemical analysis of S. asoca (bark) methanolic extract revealed the presence of high percentage of flavonoids and r...

Saraca asoca (Roxb.) De Wilde (Ashoka) is a highly valued endangered medicinal tree species from Western Ghats of India. Besides treating cardiac and circulatory problems, S. asoca provides immense relief in gynecological disorders. Higher price and demand, in contrast to the smaller population size of the plant, have motivated adulteration with other plants such as Polyalthia longifolia (Sonne...

The antimicrobial potential of seventy-seven extracts from twenty-four plants was screened against eight bacteria and four pathogenic fungi, using microbroth dilution assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Water extracts of Acacia nilot...

Saraca asoca has been traditionally used in Indian system for treatment of uterine, genital, and other reproductive disorders in women, fever, pain, and inflammation. The hypothesis of this study is that acetone extract of Saraca asoca seeds is an effective anti-inflammatory treatment for arthritis in animal experiments. The antiarthritic effect of its oral administration on Freund's adjuvant-i...

The bark of Saraca asoca is used as a main ingredient in the preparation of Asoka Arishta, a drug indigenous to Sri Lanka. In this paper an investigation on some biologically active constituents of the bark is described. ( — )-Epicatechin and procyanidin B2 were identified and a new compound, named l l ' -deoxyprocyanidin B, was found. Its structure was elucidated by means of proton-NMR.

DNA fingerprinting singly or in combination with phytochemical analysis is ideal for quality control of crude plant-based drugs. However, when the source material is tannin rich stem bark, extraction of DNA by conventional methods becomes challenging. In such cases, phytochemical profiling serves as very useful tool for its identification. The work herein described a method for simultaneous DNA...

Herbal medicines are highly complex and have unknown mechanisms in diseases treatment. Saraca asoca (Roxb.), De. Wild has been recommended to treat gynecological disorders and used in several commercial polyherbal formulations. In present study, efforts have been made to explore antimicrobial activity and its co-relation with the distributions of catechins in the organs of S. asoca using target...