Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials and Methods:Twenty-four adult male Sprague-Dawley rats were randomly divided into three groups: sham-operation (control group), sciatic nerve crush, and sciatic nerve transaction. Sciatic nerve surgery was perfor...

how to cite this article: harsh v, chengazhacherril r.b, sharmak, kalakoti p, gupta u, ahmad w, kumar a. sciatic nerve injection palsy in children. iran j child neurol. autumn 2016; 10(4):86-87.   letter to editor  pls see pdf file.   references 1. toopchizadeh v, barzegar m, habibzadeh a. sciatic nerve injection palsy in children, electrophysiologic pattern and outcome: a case series study. ir...

objective(s):  the aim of this study was to evaluate the final outcome of nerve regeneration across the eggsell membrane (esm) tube conduit in comparison with autograft. materials and methods: thirty adult male rats (250-300 g) were randomized into (1) esm conduit, (2) autograft, and (3) sham surgery groups. the eggs submerged in 5% acetic acid. the decalcifying membranes were cut into four pie...

repairing the damaged nerves caused by physical injury (trauma), is one of the major challenges facing modern medical sciences. evening primrose oil (epo) extraction of oenothera biennis seed that enriches with omega-6,γ-linoleic acid and linoleic acid that they have essential role in myelination and neural membrane structure. the aim of this study was to evaluate the functional recovery of sci...

objective(s): we investigated the histopathological effects of metamizole sodium (ms) on the sciatic nerve.  materials and methods: this study was performed using 48 adult male wistar albino rats. ten groups were constituted with 6 rats in each group. ms injection into the sciatic nerve (group 1), ms injection into the muscle [group 3 (50 mg/kg, 0.4 ml) and group 5 (50 mg/kg, 0.8 ml)], ms injec...

a 28-year-old man with neurofibromatosis type 1(nf1) presented with a tumor in the sciatic nerve and femoral nerve. the differential diagnosis of malignant peripheral nerve sheath tumor was based on clinical, radiological, and histological evidence. the tumor apparently originated in sciatic nerve at the posterior aspect of the left thigh. the lesion was resected totally without neural damage t...

background and objective: sciatic nerve transection is characterized by a rapid wave of motoneuron death associated with progressive synaptic lesions. the purpose of this study was to evaluate the long term synaptic changes. materials and methods: this basic study was carried out on paraffin- or resin-embedded tissue blocks for evaluation of synaptophysin and choline acetyl transaferase (chat) ...

introduction: repair of peripheral nerve injuries is an intensive area of challenge and research in modern reconstructive microsurgery. intensive research is being carried out to develop effective alternatives to the standard nerve autografting, avoiding its drawbacks. the aim of the study was to evaluate the effectiveness of a newly designed mechanical device for the reconstruction of the scia...