To investigate the effect of sevoflurane combined with ulinastatin on cell proliferation and migration human lung adenocarcinoma. Human adenocarcinoma cells H1975 were cultured in vitro, treated different concentrations sevoflurane, sevoflurane+ulinastatin, divided into control group, sevoflurane+ulinastatin group by counting kit 8; cycle flow cytometry; number was measured Transwell; protein i...

Purpose: To investigate the effect of eriocitrin on sevoflurane-induced neurotoxicity in mice.Methods: Mouse hippocampal neurons (HT22) were exposed to different concentrations sevoflurane for 6 h and then incubated with another 24 h. Cell viability was determined by CCK8 assay, while fluorescence intensity dichlorodihydrofluorescein used evaluate reactive oxygen species. Enzyme linked immunoso...

background: emergence delirium (ed) is a frequent postoperative complication in children. its prevalence is about 25-80% and is observed more commonly with rapid-acting volatile anesthetics than the older inhalation agents. methods: 30 patients aging between 2 to 8 years were included in this randomized double blind study. we compared the effect of combination of two anesthetic drugs, propofol-...


 Purpose: To investigate Curcuma longa Linn against neuronal damage induced by exposure to sevoflurane during surgical procedures.
 Methods: A sealed box made of transparent glass was used for anaesthetic neurons. The neurons were exposed at doses 1.5, 3, 6 and 12 μM prior viability assessment using MTT assay. effect treatment on protein expression determined western blotting.
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Approximately 95% of the anesthetic gas administered to a patient is exhaled and ultimately released into atmosphere. Most gases have high global warming potential so this approach adds significantly greenhouse footprint. In work, we develop feasible means capture such an (sevoflurane) before it hospital scavenging system that retained within circuit. Sevoflurane using microporous 1,2-bis(triet...

PURPOSE . Sevoflurane, one of the most used general anesthetics, is widely used in clinical practice all over the world. Previous studies indicated that sevoflurane could induce neuron apoptosis and neural deficit causing query in the safety of anesthesia using sevoflurane. The present study was designed to investigate the effects of sevoflurane on electrophysiology in Drosophila pupa whose exc...

BACKGROUND Original sevoflurane (Sevofrane) contains a small amount of water, which can inhibit the production of hydrofluoric acid. Hydrofluoric acid is highly pungent, and sevoflurane that contains a high concentration of hydrofluoric acid is not suitable for volatile induction of anaesthesia. Recently, generic sevoflurane (Sevoness) has become available in some countries. The generic product...

results the mean heart rate values were significantly less in the sevoflurane group (p value < 0.05) at 25 minutes after the surgery. the mean blood pressure in the isoflurane group was significantly higher compared with the sevoflurane group in 10, 20 and 30 minutes after the surgery (p values = 0.0131, 0.0373 and 0.0028, respectively). these differences were clinically unimportant because hea...

BACKGROUND The purpose of this study was to compare cardiac sympathetic and parasympathetic balance using heart rate variability (HRV) during induction of anaesthesia between sevoflurane and isoflurane in combination with nitrous oxide. METHODS 40 individuals aged from 30 to 60 years, scheduled for general anaesthesia were equally divided into sevoflurane or isoflurane groups. After 100% oxyg...