mammalian expression systems, due to their capacity in post-translational modification, are preferred systems for biopharmaceutical protein production. several recombinant protein systems have been introduced to the market, most of which are under clinical development. in spite of significant improvements such as cell line engineering, introducing novel expression methods, gene silencing and pr...

In this paper, a study of the perceived destination image created by promotional Web Pages is expounded in an attempt to identify their differences as generators of destination image in the consumers' mind. Specifically, it seeks to analyse whether the web sites of different Spanish regions improve the image that consumers have of the destination, identifying their main dimensions and analysing...

distribution and stability of purple nutsedge (cyperus rotundus) population within four fields under corn-fallow rotation were analyzed over two growing seasons in 2005 and 2006 at the agricultural research station of ferdowsi university, mashhad, iran. in 2005, n-fertilizer (urea) was applied at two different application methods (whole and split application). as a result of applying or not app...

The restriction site mutation (RSM) assay was used to study the mutational sensitivities of three target regions of the murine p53 gene. The non-coding intron 6 target region was compared with the coding regions exon 4 and exon 5 with respect to their relative sensitivity to the induction of mutations by 1,2-dimethylhydrazine (DMH). Our results demonstrated that the majority of induced mutation...

Understanding the evolution, and managing the reengineering of a large Web site is as hard as evolving a large software system of comparable size. Evolution and maintenance of traditional legacy systems have been extensively studied by reengineering researchers. However, Web site evolution and migration is a new domain with many open questions. We propose the development of a Web site architect...

The Internet increasingly serves as a platform for the delivery of public health interventions. The efficacy of Internet interventions has been demonstrated across a wide range of conditions. Much more work remains, however, to enhance the potential for broad population dissemination of Internet interventions. In this article, we examine the effectiveness of Internet interventions, with particu...

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