gum tragacanth is a natural complex mixture of polysaccharides and alkaline minerals extracted from species of astragalus plant, which is found widely in arid regions of the middle east. in a pilot experimental study we examined the effects of its topical application on wound healing in ten albino adult male rats. two similar parasagittal elliptical full-thickness wounds (control vs. test sampl...

background: this study was designed to investigate the efficacy of pentoxifylline (ptx) in the treatment of irradiated wounds. materials and methods: ten female pigs of the large white strain were used in these investigations. six skin fields, 4 * 4 cm and separated from each other by 4 cm, were marked out on each flank and those on left flank were irradiated with 18gy single dose of 250 kv x-r...

objective(s) the process of wound healing involves tightly integrated events including inflammation, granulation tissue formation and remodeling. systemic administration of l-arginine promotes wound healing but its global side effects are undesirable. to confine the action of l-arginine at the site of injury, we tested the effects of local administration of l-arginine on the healing of excision...

healing of skin wound is a multi-factorial and complex process. proper treatment of diabetic wounds is still a major clinical challenge. although diabetes mellitus can occur in ruminants, healing of wounds in diabetic ruminants has not yet been investigated. the aim of this study was to evaluate healing of ovine excisional diabetic wound model. eight 4-month-old iranian makoui wethers were equa...

the microorganisms have been noted as the main cause of delayed wound healing.the most common pathogen causing the wound infections is staphylococcus aureus. silver nanoparticles (agnps) show ample antibacterial activities. in the present study, the effect of agnps on mouse wounds inoculated with s. aureus was investigated. sixty male mice (20 to 30 g) were anesthetized, full-thickness skin wou...

background previous reports have shown that quince seed might have some healing effects on skin ulcers in rabbits. objectives to assess the potential healing effect of quince seed cream on human skin ulcers. patients and methods the present study was a double-blind, randomized, controlled trial. fifty patients with skin ulcer caused by disposable biopsy punch 5 mm were allocated in two groups (...

wound healing in the skin depends upon the availability of appropriate trace metals as enzyme cofactors and structural components in tissue repair. the present study is a part of a series of experimental investigations to examine the influence of bentonite on skin wound healing. surgically induced skin wounds in 48 young adult male rats were exposed topically to bentonite (12 round wound and 12...

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mesenchymal stem cells (mscs) could differentiate into various types of tissues. these cells serve as a backup for the regeneration and repair of tissues or cells after injury. a skin wound is defined as an injury to the skin that needs to be restored. all types of cells in skin especially mesenchymal stem cells play important role in wound healing process. in particular, paracrine signaling of...

background and objectives: the wounds are still the health tribulations at the present time. in the present research the effect of a new herbal ointment (oppyheal) in treatment of rat’s wound has been investigated. the effectiveness of the ointment was compared with the fibrinolysin/dnase. methods: fifty four male wistar rats were used. the wound was created on the back cervical skin of the ani...