The rate of denaturation of hemaglobin and other proteins by mechanical shaking is strongly affected by organic solvents. A group pf solvents,including alcohols and ketones, was found to stabilize proteins at low concentrations, although these same organic solvents denatured proteins at high concentrations. The stabilizing effect of alcohols increased with increasing chain lenghts. The second g...

Organic solvent, Enzymatic Hydrolysis, Cellulose, Acceleration Effect, Glucose Yield Effect of organic solvents on enzymatic hydrolysis of celluloses was studied. It was found that toluene and xylene can accelerate the rate of the enzymatic hydrolysis reaction of filter paper and cellulose powder. The addition of N,N-dimethylformamide, acetone, and alcohols was negative effect for the enzymatic...

In this review, the effect of organic solvents on microalgae cultures from molecular to industrial scale is presented. Traditional organic solvents and solvents of new generation-ionic liquids (ILs), are considered. Alterations in microalgal cell metabolism and synthesis of target products (pigments, proteins, lipids), as a result of exposure to organic solvents, are summarized. Applications of...

background: exposure to organic solvents is common among workers. objective: to assess neurobehavioral effects of long-term exposure to organic solvents among rubber workers in tehran, iran. methods: across-sectional study was conducted on 223 employees of a rubber industry. the participants completed a data collection sheet on their occupational and medical history, and demographic characteris...

The catalytic activity of cytochrome P450 enzymes is known to be affected by presence of organic solvents in in vitro assays. However, these effects tend to be variable and depend on the substrate and CYP450 isoform in question. In the present study, we have investigated effect of ten water miscible organic solvents (methanol, ethanol, propanol, isopropanol, acetone, acetonitrile, dimethylsulph...

Measurements of two-photon-excited fluorescence (TPF) of fluorescein and Rhodamine 6G in various solvents were performed with a continuous-wave (cw) laser for excitation and an acousto-optic tunable filter for spectral dispersion. Interestingly, the cw laser excitation produced an unwanted thermal-lens effect when the measurements were performed in solvents that absorb the excitation laser ligh...

The chemical sector is the third largest industry in Europe. There is increasing evidence from epidemiological and clinical studies that occupational exposures to organic solvents may have detrimental effect on hearing. Most of the literature data concern one of the three following types of exposure to industrial solvents: mixed solvent exposure (the most common type); styrene-only exposure; an...

Organic solvents used for solubilization of the substrates/NCEs are known to affect the activity of cytochrome P450 enzymes. Further, this effect varies with the solvents used, the substrates and CYP450 isoforms in question. In the present study, we have investigated the effect of ten commonly used water miscible organic solvents (methanol, ethanol, 1-propanol, 2-propanol, acetonitrile, acetone...

introduction: hearing loss is one of the most common occupational diseases. in most workplaces, workers are exposed to noise and solvents simultaneously, so the potential risk of hearing loss due to solvents may be attributed to noise.  in this study we aimed to assess the effect of exposure to mixed aromatic solvents on hearing in the absence of exposure to hazardous noise.   materials and met...

in this study, the fluorogenic efficiency of fluorescamine for spectrofluorimetric analysis of primary amines was investigated. different mixtures of dichloromethane and other organic solvents were used for evaluation of fluorescence stability and intensity of fluorescamine derivative (pyrrolinone). solvents such as acetonitrile (acn), tetrahydrofuran (thf) and dioxane increase stability and in...