objective(s):leptin is a novel and interesting hormone for anyone trying to lose weight, but its effects on male gonad structure in longitudinal study is unknown. the present study was designed to explore morphometrical changes of mouse testicular tissue after long-term administration of leptin. materials and methods:thirty healthy mature male mice were randomly assigned to either control (n=15...

AIM The aim of this study was to investigate the morphological and functional features of the process of spermatogenesis in the testes of male albino rats when exposed to lead acetate. MATERIALS AND METHODS Using histological, morphometric and statistical methods explored the effects of lead acetate on the process of spermatogenesis in the testes of male albino rats. Investigations were carri...

Background: Methamphetamine (mAMP) as a recreational drug has devastating effects on the central nervous system (CNS). Several studies have shown that mAMP has inhibitory effects on oogenesis and spermatogenesis, and causes impaired fertility. This study designed to investigate the effect of mAM Padministration on histological changes and spermatogenesis indices in the testis of adult male rats...

Background: Saffron is widely used as a food flavor and has well known medicinal effects which have an effect on steroid and sexual hormones. The aim of present study was investigation of saffron orally administration on spermatogenesis index in stress induced rats. Materials and Methods: In present study, 160 male adult rats divided to four groups with 10 rats per each cage and with four repli...

Background: Opium, as the most widely known opioid in the world, has significant effects on reproductive organs, which can affect fertility and influence the next generation. This study was performed to investigate the effects of opium administration on histological changes and spermatogenesis indexes in the testis of adult male rats. Methods:A total of 50 adu...

One hundred one azoospermic males were subjected to fine needle aspiration cytology (FNAC) of the testis and 11 of them underwent testicular biopsy as well. In 99 cases, the aspiration was adequate for classifying into different categories, which are as follows: Sertoli cell only syndrome (46), normal spermatogenesis (27), hypospermatogenesis (10), tubular/peritubular sclerosis (10) and maturat...

The assessment of the indicators reproductive potential male white rats exposed to smoke for 1 month was carried out. Examination animals included determination spermatogenesis index and level DNA fragmentation methylation in testes blood. A statistically signifi-cant increase genome-wide blood revealed. morphometric study testis tissue revealed a violation indices rats.

We investigated spermatogenic damage induced by anti-cancer agents in previous studies. The results showed that the damage to spermatogenesis induced by anti-cancer agents could be due to not only direct damaging effects on DNA synthesis but also a direct effect on Sertoli cell function. Thus, stimulating Sertoli cell function could protect against the damaging effects of anti-cancer agents on ...

This study aimed to elucidate seasonal reproductive patterns by associating the immunolocalization of steroidogenic enzymes responsible for estrogen and androgen synthesis, cytochromes P450 aromatases (P450 arom), 17-hydroxylase/17,20-lyase (P450c17) respectively, as well redox partner NADPH cytochrome oxido-reductase (CPR) in male mud turtle (Kinosternon scorpioides). The animals were collecte...