objective(s) high blood glucose induces molecular, cellular, morphological and behavioral changes in the brain. metabolic disturbances, contribute to the hippocampus injury and development of partial focal seizures. the aim of this study was to investigate the effects of infantile repeated hyperglycemia on neuronal density of hippocampal ca3region in newborn wistar male rats and its effect on c...

OBJECTIVE The aims of this study were to analyze the relevant methods of computed tomography (CT) and stereology with respect to the estimation of tumor volume and to determine whether the response rates measured by the stereological method correlate with those of conventional morphometric techniques in lung cancer. MATERIALS AND METHODS The study group was composed of 32 patients, including ...

A stereological method is described for estimating the distribution of grain-boundary types in polycrystalline materials on the basis of observations from a single planar section. The grain-boundary distribution is expressed in terms of five macroscopically observable parameters that include: three parameters that describe the lattice misorientation across the boundary and two parameters that d...

BACKGROUND AND AIMS Validation of non-invasive methods of liver fat quantification requires a reference standard. However, using standard histopathology assessment of liver biopsies is problematical because of poor repeatability. We aimed to assess a stereological method of measuring volumetric liver fat fraction (VLFF) in liver biopsies and to use the method to validate a magnetic resonance im...

In order to develop a reliable and sensitive method for studying the development and progression of pulmonary emphysema, we compared stereological indices with the usual index for grade of emphysema, i.e., the mean linear intercept (Lm), in elastase-induced emphysema in mice. The Lm and stereological indices, including volumes of total lung tissue (V(lt)), airspaces (V(air)), and surface area o...

Using an unbiased stereological technique, the total numbers of pigmented and non-pigmented neurons were estimated in the substantia nigra of seven patients with Parkinson's disease and seven control patients. Compared with the controls, in which the average total number of pigmented neurons was 550,000, the number of neurons was reduced by 66% in the patients. The average total number of non-p...

in pancreatic survey, quantitative and morphological characteristics could be fundamental variables for the evaluation of some structures. the aim of this study was the application of stereological methods for estimation of quantitative parameters and morphological evaluation of the pancreas in chickens. ten adult male and ten adult female native chickens were used in this study. routine tissue...

Alteration in capacity and function of proximal distal convoluted tubules kidney exposed by Molybdenum trioxide nanoparticles female rats (Stereological technique)

The aim of this retrospective pilot study was to evaluate the Aperio nuclear V9 algorithm as an image analysis tool to observe the histopathological changes of ocular surface squamous neoplasia (OSSN). A histopathological assessment, including the Ki-67 proliferative index (PI) of immunohistochemically-stained tumor conjunctiva (TC) and healthy conjunctiva (HC) tissues, was performed in six cas...

In pancreatic survey, quantitative and morphological characteristics could be fundamental variables for the evaluation of some structures. The aim of this study was the application of stereological methods for estimation of quantitative parameters and morphological evaluation of the pancreas in chickens. Ten adult male and ten adult female native chickens were used in this study. Routine tissue...