Introduction: Proton therapy delivers radiation to tumor tissue in a much more confined way than conventional photon therapy thus allowing the radiation oncologist to use a greater dose while still minimizing side.   Materials and Methods: protons release most of their energy within the tumor region. As a result, the treating physician can potentially give an...

Introduction: Proton therapy is a type of radiation treatment that it uses protons to treat cancer. Because of the protons’ unique ability to distribute the radiation dose more directly to the tumor, it minimizes the damage to nearby healthy tissues. The rate of energy loss by the ion in the target is called stopping power. The total stopping power is sum nuclear and electroni...

The purpose of this study was to evaluate proton depth dose perturbation caused by a radio-opaque hydrogel fiducial marker. Electronic proton stopping powers in the hydrogel were calculated for energies 0.5-250 MeV, and Monte Carlo simulations were generated of hydrogel vs. gold markers placed at various water phantom depths in a generic proton beam. Across the studied energy range, the gel/wat...

Objective: We introduce a new treatment verification technique to estimate the primary particle’s stopping power from prompt gamma timing measurements in proton therapy. Approach: The starting point is Spatio-temporal Emission Recostruction technique, which provides time-depth distribution of emitted photons with multiple Prompt-Gamma Timing detector setup based on Lanthanum Bromide crystals. A...

Proton computed tomography (CT) has been described as a solution for imaging the proton stopping power of patient tissues, therefore reducing the uncertainty of the conversion of x-ray CT images to relative stopping power (RSP) maps and its associated margins. This study aimed to investigate this assertion under the assumption of ideal detection systems. We have developed a Monte Carlo framewor...

Proton radiography and tomography have long promised benefit for proton therapy. Their first suggestion was in the early 1960s and the first published proton radiographs and CT images appeared in the late 1960s and 1970s, respectively. More than just providing anatomical images, proton transmission imaging provides the potential for the more accurate estimation of stopping-power ratio inside a ...

The use of high-energy proton beams enables to delivering high doses to target volumes, while sparing organs at risk compared to X-ray radiotherapy. However, the protons advantages cannot be fully exploited because the range (i.e the stopping powers) of protons in matter is not accurately known. Indeed, the proton stopping powers are obtained by an empirical conversion of X-CT Hounsfield Units ...