نتایج جستجو برای: TCF

تعداد نتایج: 1914  

 فریدون معماری, ,  ماندانا زنگنه, , جهانگیر رأفت, , زهرا صدیقی, , صنمبر صدیقی, , علی منتظری, , علیرضا موسوی‌جراحی, , محمدعلی محققی, , مریم مستقیمی‌تهرانی, ,

Background: This prospective phase III study was designed to compare the activity of two combinations chemotherapy drugs in advanced gastric adenocarcinoma Methods: In a double blinded clinical trial, From Jan. 2002 to Jan. 2005, ninety patients with advanced gastric adenocarcinoma were randomly assigned to 1) Cisplatin and continuous infusion of 5FU and Epirubicin (ECF), and 2) Cisplatin and ...

Journal: :Coatings 2023

As transparent heated films (THFs) based on conductive oxides (TCOs) are restricted by expensive raw materials and inappropriate fabricating film curved surfaces because of its brittleness, silver nanowires (AgWS-TCF) is an ideal alternative material for THF. However, there still many problems to be solved in the electrical thermal stability AgNWs-TCF. In this paper, Al-doped ZnO (AZO) nanopart...

Journal: :Journal of Chemical Physics 2021

We present the non-adiabatic Matsubara dynamics, a general framework for computing time-correlation function (TCF) of electronically systems. This new formalism is derived based on generalized Kubo-transformed TCF using Wigner representation both nuclear degrees freedom and electronic mapping variables. By dropping non-Matsubara normal modes in quantum Liouvillian explicitly integrating these o...

2010
Guodong DING Shufang ZHOU Ying TIAN Rong SHI

Trichlorfon (TCF) is a widely used broad-spectrum agricultural organophosphate (OP) pesticide. Few studies have evaluated the effects of TCF on reproductive toxicity after low-level exposure, especially after long-term exposure. This study assessed the direct effects of TCF on estrous cycle, oocyte maturation in female mice, and developmental outcome in nearterm fetuses after 30 consecutive day...

Journal: :Global and Planetary Change 2022

We have analyzed the teleconnection of total cloud fraction (TCF) with global sea surface temperature (SST) in multi-model ensembles (MME) fifth and sixth Coupled Model Intercomparison Projects (CMIP5 CMIP6). CMIP6-MME has a more robust realistic (TCF SST) pattern over extra-tropics (R ~ 0.43) North Atlantic 0.39) region, which turn resulted an improvement rainfall bias Asian summer monsoon (AS...

2011
Jian Ma Ruiqing Wang Xianfeng Fang Yan Ding Zuoming Sun

Overwhelming activation of IL-17, a gene involved in inflammation, leads to exaggerated Th17 responses associated with numerous autoimmune conditions, such as experimental autoimmune encephalomyelitis (EAE). Here we show that TCF-1 is a critical factor to repress IL-17 gene locus by chromatin modifications during T cell development. Deletion of TCF-1 resulted in increased IL-17 gene expression ...

2003
Mariette Oosterwegel Marc van de Wetering Katia Georgopoulos

CD3-e gene expression is confined to the T cell lineage. We have recently identified and cloned a human transcription factor, TCF-1, that binds to a functional element in the T lymphocyte-specific enhancer of CD3-e . In a panel of human cell lines, TCF-1 expression was restricted to T lineage cells . TCF-1 belonged to a novel family of genes that contain the so-called high mobility group 1 (HMG...

Journal: :Mechanisms of Development 1998
Eun Ah Cho Gregory R Dressler

The Tcf family of transcription factors, in association with beta-catenin, mediate Wnt signaling by transactivating downstream target genes. Given the function of wnt genes in neural development and organogenesis, Tcf transcription factors must be integral to the development of many embryonic tissues. In fact, the role of Tcf genes in axis formation in Xenopus and in segment polarity in Drosoph...

Journal: :The Journal of infectious diseases 2004
A Mocroft B Ledergerber J P Viard S Staszewski M Murphy A Chiesi A Horban A-B E Hansen A N Phillips J D Lundgren

OBJECTIVE The purpose of the present study was to determine the prevalence and incidence of virological triple drug-class failure (TCF) and to summarize the clinical outcome for patients who started receiving highly active antiretroviral therapy (HAART). METHODS The present study is an observational longitudinal study of 3496 treatment-experienced (TE) and treatment-naive (TN) patients monito...

Journal: :Journal of immunology 2006
Zhaofeng Huang Huimin Xie Vassilio Ioannidis Werner Held Hans Clevers Maureen S Sadim Zuoming Sun

By interacting with MHC class II molecules, CD4 facilitates lineage development as well as activation of Th cells. Expression of physiological levels of CD4 requires a proximal CD4 enhancer to stimulate basic CD4 promoter activity. T cell factor (TCF)-1/beta-catenin pathway has previously been shown to regulate thymocyte survival via up-regulating antiapoptotic molecule Bcl-xL. By both loss and...

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