نتایج جستجو برای: Tacrolimus

تعداد نتایج: 9146  

Background and Aim: Application of topical tacrolimus in Vernal Keratoconjunctivitis is considered as an alternative to steroids. Due to the low aqueous solubility of the drug, preparing a solution of the drug has got particular importance. In the present study, tacrolimus eye drop was prepared using cyclodextrin, as a drug solubility enhancer. Materials and Methods: To improve the aqueous s...

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

Tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. To date, there is no information on the pharmacokinetics of tacrolimus in Iranian liver transplant recipients. This study was designed to determine pharmacokinetic properties of orally administe...

Journal: :iranian journal of pharmaceutical research 0
zahra nasiri-toosi pharmacist, faculty of pharmacy, tehran university of medical sciences, tehran, iran. simin dashti-khavidaki 1- associate professor of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran. 2- nephrology research center, tehran university of medical sciences, tehran, iran. mohsen nasiri-toosi associate professor of gastroenterology, imam khomeini hospital complex, tehran university of medical sciences, tehran, iran. ali jafarian associate professor of surgery, imam khomeini hospital complex, tehran university of medical sciences, tehran, iran. hossein khalili professor of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran. shirinsadat badri assistant professor of clinical pharmacy, faculty of pharmacy, isfahan university of medical sciences, isfahan, iran.

tacrolimus, a cornerstone of immunosuppressive therapy in solid organ transplantation, has a narrow therapeutic range with considerable inter-individual and intra-individual pharmacokinetic variability. to date, there is no information on the pharmacokinetics of tacrolimus in iranian liver transplant recipients. this study was designed to determine pharmacokinetic properties of orally administe...

Journal: :thrita 0
zahra tolou-ghamari isfahan urology and renal transplantation research center, al-zahra research centers, isfahan university of medical sciences, isfahan, ir iran; isfahan neurosciences research centre and isfahan urology and renal transplantation research center, al-zahra research centers, isfahan university of medical sciences, isfahan, ir iran. tel: +98-3137922591, fax: +98-313668001 behnam sanei department of general surgery, saint alzahra hospital, isfahan university of medical sciences, isfahan, ir iran

conclusions in the iranian population of organ transplantation polypharmacy should be based on a rational basis of scheduled therapeutic drug monitoring. to confirm the presence of a correlation between prograf levels with early or late rejection, nephrotoxicity or neurotoxicity, further studies in a greater number of liver recipients are recommended. patients and methods based on a cross-secti...

Background and aims: Immunosuppressive regimens are a key component for successful kidney transplantation. This systematic review aimed to assess the efficacy and safety of combination therapy of everolimus with tacrolimus in kidney transplantation recipients. Methods: Results were limited to English-language articles. Trials where recipients received ano...

ژورنال: پوست و زیبایی 2011
حصوری, سهیلا, خاتمی, علیرضا, زرتاب, حامد, صادقی, فریبرز, عطارد, عسل, فیروز, علیرضا, منصوری, پروین, چلنگری, رضا, چلنگری, کاتالین,

Background and Aim: Atopic dermatitis (AD) is a chronic, relapsing, pruritic skin disease more common in infancy and childhood. Emollients, topical corticosteroids, and avoidance of irritating factors are the mainstay of its treatment, but fear of side effects has limited the use of topical corticosteroids. The objective of this study was to evaluate the safety and efficacy of topical tacrolimu...

Journal: :journal of reports in pharmaceutical sciences 0
mohammad bagher majnooni mohammad bagher gholivand mehdi khodadadian nazanin-sadat afnanzade gholamreza bahrami

the adsorptive behavior of the immunosuppressive agent tacrolimus was studied by cyclic and differential-pulse voltammetry on a hanging mercury drop electrode (hmde). the drug was accumulated at hmde and two well-defined peak currents were obtained at -1353 and -1417 mv vs . sce (saturated kcl) in borate buffer (ph 10.0) + 0.1 kcl solution. a voltammetric procedure was developed for the determi...

Journal: :international journal of epidemiology research 0
morteza arab zozani iranian center of excellence in health management, tabriz university of medical sciences, tabriz, i.r. iran mitra mahdavi-mazdeh iranian tissue bank and research center, tehran university of medical sciences, tehran, i.r. iran sayed alireza hosseini committee of clinical research, food and drug administration, tehran, i.r. iran reza majdzadeh school of public health and knowledge utilization research center, tehran university of medical sciences, tehran, i.r. iran ali akbari sari health management and economics dept., tehran university of medical sciences, tehran, i.r. iran

background and aims: immunosuppressive regimens are a key component for successful kidney transplantation. this systematic review aimed to assess the efficacy and safety of combination therapy of everolimus with tacrolimus in kidney transplantation recipients. methods: results were limited to english-language articles. trials where recipients received another regimen were excluded. the cochrane...

Journal: :journal of paramedical sciences 0
dariyush raeisi faculty of medicine, kermanshah university of medical sciences, kermanshah hamidreza omrani faculty of medicine, kermanshah university of medical sciences, kermanshah farid najafi faculty of public health, kermanshah university of medical sciences, kermanshah abdolreza mahruei faculty of medicine, kermanshah university of medical sciences, kermanshah farhad shavisizadeh medical genetics department, shahid beheshti university of medical sciences, tehran mohammad erfan zare student research committee, kermanshah university of medical sciences, kermanshah

kidney transplantation is the most common transplantation in the world. annually, a large number of patients that have chronic renal failure are undergoing renal transplantation and the major subject about these patients is the rejection of graft that should be controlled by immunosuppressive agents.  the aim of this study is investigation of the effect of cyclosporin against tacrolimus in pati...

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