abstract: antibiotics are a valuable addition to health practitioners for the management of bacterial infections. during endodontic treatment and when managing trauma to the teeth, antibiotics may be applied systemically or locally. due to the potential risk of adverse effects of systemic applications, and the ineffectiveness of systemic prescribed antibiotics in necrotic or pulpless teeth and ...

tetracycline may be used to treat several types of bacterial diseases in ruminants. in addition, tetracycline is added to food to promote the growth. there are few reports on the pharmacokinetics of tetracycline in sheep. therefore, the objective of this study was to examine the pharmacokinetic characteristics of the drug in sheep. ten apparently healthy mixed-breed sheep were administered 20 m...

in this assay, edible cattle tissues from local markets of ardabil, a province of iran, were examined for residues of tetracycline antibiotics (tetracycline, oxytetracycline and chlortetracycline). in total, 110 samples of triceps, gluteal muscle, diaphragm, kidney and liver were randomly obtained from the local markets of the city of ardabil. solid-phase extraction (spe) and high-performance l...

the aim of the present study was to determine the protective action of silymarin on acute toxicity due totetracycline severe overdose in cats. thirty healthy cats were randomly allotted into five equal groups. catsin group a were given tetracycline (single dose 120 mg⁄kg, p.o.); group b consisted of cats that receivedsilymarin (single dose 30 mg⁄kg, p.o.) concurrent with tetracycline administra...

objective: in recent years, antibiotics have been used widely in the glob to prevent and treat bacterial diseases. they injected into eggs to eliminate pathogens and prevention of egg transmission of disease, but the adverse effects of drugs have always been a major concern. there is little information available about the safety of tetracycline drugs in the embryonated eggs of the birds. the ob...

background mercury is one of the most toxic heavy metals. even a small amount of it is toxic for all living organisms. some of bacteria have developed special resistance mechanisms against mercury, in addition to resistant to different antibiotics. these bacteria usually acquire hg and antibiotic resistance genes via horizontal gene transfer in their habitat. objectives the aim of this study wa...

tetracyclines are broad spectrum antibiotics which are inexpensive and widely available and have an appropriate safety profile. in addition to antibiotical effects, tetracyclines can inhibit matrix metaloproteinase and collagenase, and subsequently reduce inflammation, angiogenesis, and neovascularization. they have partial neuro-protective, anti-apoptotic and antioxidant properties. given thes...

conclusions the high prevalence of tet (o) resistance gene along with new detection of tet (a) resistance gene in campylobacter spp. isolated from poultry carcasses revealed an extensive tetracycline resistance among campylobacter isolates from poultry in iran. it emphasized the need for cautious use of tetracycline in poultry production to decrease the extension of tetracycline-resistant campy...

six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. blood samples were collected before and at various time intervals after the administration of the drug. serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. non...